6'-羟基二氢螺[环己烷-1,2'-呋喃并[3,4-d][1,3]二氧杂环戊烯]-4'(3a'H)-酮 | 85029-84-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 6'-羟基二氢螺[环己烷-1,2'-呋喃并[3,4-d][1,3]二氧杂环戊烯]-4'(3a'H)-酮
• 英文名称: (-)-2,3-Cyclohexylidene-L-erthuronic acid
• 英文别名: 6-hydroxyspiro[6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-2,1'-cyclohexane]-4-one
• CAS: 85029-84-1
• 化学式: C₁₀H₁₄O₅
• mdl: MFCD00040503
• 分子量: 214.21
• InChiKey: GHGRKHAVPBZSIH-UHFFFAOYSA-N

物化性质

• 沸点：
  438.6±45.0 °C(Predicted)
• 密度：
  1.39±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  65
• 氢给体数：
  1
• 氢受体数：
  5

安全信息

• 海关编码：
  2932999099

文献信息

• [EN] COMPOUNDS, REAGENTS, AND USES THEREOF<br/>[FR] COMPOSÉS, RÉACTIFS ET UTILISATIONS ASSOCIÉES
  申请人：METABOLON INC

  公开号：WO2019067699A1

  公开（公告）日：2019-04-04

  The present invention provides a compound of formula (I), formula (II), formula (III), (IV) or a salt thereof, compositions and methods of making the compound, methods and reagents for measuring the compound, and kits using the same. The use of a compound of formula (I), formula (II), formula (III), or formula (IV) for assessing or monitoring kidney function in a subject, determining predisposition to developing reduced kidney function, classifying a subject according to level of kidney function, and diagnosing or monitoring chronic kidney disease is also described.

  本发明提供了式(I)、式(II)、式(III)、(IV)或其盐的化合物，以及制备该化合物的组合物和方法，测定该化合物的方法和试剂，以及使用该化合物的工具包。还描述了使用式(I)、式(II)、式(III)或式(IV)的化合物来评估或监测受试者的肾功能，确定发展肾功能减退的易感性，根据肾功能水平对受试者进行分类，以及诊断或监测慢性肾脏疾病。
• COMPOUNDS, REAGENTS, AND USES THEREOF
  申请人：Metabolon, Inc.

  公开号：US20200231541A1

  公开（公告）日：2020-07-23

  The present invention provides a compound of formula (I), formula (II), formula (III), (IV) or a salt thereof, compositions and methods of making the compound, methods and reagents for measuring the compound, and kits using the same. The use of a compound of formula (I), formula (II), formula (III), or formula (IV) for assessing or monitoring kidney function in a subject, determining predisposition to developing reduced kidney function, classifying a subject according to level of kidney function, and diagnosing or monitoring chronic kidney disease is also described.