19-(Bromomethyl)octatriaconta-9,29-diene-18,21-dione

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 19-(Bromomethyl)octatriaconta-9,29-diene-18,21-dione
• 英文别名: 19-(bromomethyl)octatriaconta-9,29-diene-18,21-dione
• 化学式: C₃₉H₇₁BrO₂
• 分子量: 651.9
• InChiKey: GRQKZBCBKAXEQA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  15.3
• 重原子数：
  42
• 可旋转键数：
  34
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS
  申请人：novosom AG

  公开号：EP2211840A2

  公开（公告）日：2010-08-04
• [EN] IMPROVEMENTS IN OR RELATING TO AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS<br/>[FR] PERFECTIONNEMENTS AUX OU SE RAPPORTANT AUX LIPOSOMES AMPHOTÈRES COMPRENANT DES LIPIDES NEUTRES
  申请人：NOVOSOM AG

  公开号：WO2009047006A2

  公开（公告）日：2009-04-16

  An amphoteric liposome comprising neutral lipids wherein said neutral lipids are selected from the group comprising cholesterol or mixtures of cholesterol and at least one neutral or zwitterionic lipid and wherein K (neutral) of said mixtures is 0.3 or less. Said amphoteric liposome may encapsulate an active agent, such as nucleic acid therapeutics. Also disclosed are pharmaceutical compositions comprising said amphoteric liposomes as a carrier for the delivery or targeted delivery of active agents or ingredients.