(2S,3R,4R,5R)-3,4,5-trihydroxy-2-methoxy-4-methylhexanal

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3R,4R,5R)-3,4,5-trihydroxy-2-methoxy-4-methylhexanal
• 化学式: C₈H₁₆O₅
• 分子量: 192.21
• InChiKey: KYHJRJIABDEAPE-WCTZXXKLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• MULTIVALENT LIGAND-LIPID CONSTRUCTS
  申请人：Bovin, Nicolai Vladimirovich

  公开号：EP3221337A1

  公开（公告）日：2017-09-27
• FORMULATIONS COMPRISING A COMBINATION OF MRI CONTRAST AGENTS
  申请人：GE Healthcare AS

  公开号：EP3383441A1

  公开（公告）日：2018-10-10
• [EN] MULTIVALENT LIGAND-LIPID CONSTRUCTS<br/>[FR] CONSTRUCTIONS LIGAND-LIPIDE MULTIVALENTES
  申请人：BOVIN NICOLAI VLADIMIROVICH

  公开号：WO2016080850A1

  公开（公告）日：2016-05-26

  Water dispersible, multivalent ligand-lipid constructs that spontaneously and stably incorporate into membranes are disclosed.
• [EN] FORMULATIONS COMPRISING A COMBINATION OF MRI CONTRAST AGENTS<br/>[FR] FORMULATIONS COMPRENANT UNE COMBINAISON D'AGENTS DE CONTRASTE POUR IRM
  申请人：GE HEALTHCARE AS

  公开号：WO2017093336A1

  公开（公告）日：2017-06-08

  The present invention relates to in vivo imaging and in particular to magnetic resonance imaging (MRI). Provided by the present invention is a pharmaceutical formulation suitable for use in an MRI procedure and which offers advantages over known such formulations. A particular dose of the pharmaceutical formulation of the invention is also envisioned as well as the use of said dose in a method of in vivo imaging. This present invention provides for simultaneous administration of a liver specific agent and a second MR contrast agent that is capable of better/further enhancing the dynamic vascular phase in a patient. The method of the invention has the advantage of simplicity and patient comfort, compared to sequential injections. Furthermore, the method of the invention provides the advantage that it can enable a lower cumulative dose of contrast agents.