2-(2-Imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-iodophenyl)ethanone

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(2-Imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-iodophenyl)ethanone
• 化学式: C₁₅H₁₅IN₂OS
• 分子量: 398.3
• InChiKey: JMRBCEKFPVWNGO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  69.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Use of P53 inhibitors for the treatment of side effects of cancer therapy
  申请人：BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

  公开号：EP1797880A2

  公开（公告）日：2007-06-20

  The therapeutic use of temporary p53 inhibitors in the treatment of p53-mediated diseases, conditions, and injuries is disclosed.

  本研究公开了临时 p53 抑制剂在治疗 p53 介导的疾病、病症和损伤中的治疗用途。
• p53 Inhibitors and therapeutic use of the same
  申请人：The Board of Trustees of the University of Illinois

  公开号：US20020019425A1

  公开（公告）日：2002-02-14

  The therapeutic use of temporary p53 inhibitors in the treatment of p53-mediated diseases, conditions, and injuries is disclosed.

  本研究公开了临时 p53 抑制剂在治疗 p53 介导的疾病、病症和损伤中的治疗用途。
• p53 inhibitors and therapeutic use of the same
  申请人：The Board of Trustees of the University of Illinois

  公开号：US20020006941A1

  公开（公告）日：2002-01-17

  The therapeutic use of temporary p53 inhibitors in the treatment of p53-mediated diseases, conditions, and injuries is disclosed.

  本研究公开了临时 p53 抑制剂在治疗 p53 介导的疾病、病症和损伤中的治疗用途。
• USE OF p53 INHIBITORS FOR THE TREATMENT OF SIDE EFFECTS OF CANCER THERAPY
  申请人：THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

  公开号：EP1143943B1

  公开（公告）日：2007-12-12
• p53 Inhibitors and Therapeutic Use of the Same
  申请人：Gudkov Andrei V.

  公开号：US20080161426A1

  公开（公告）日：2008-07-03

  The therapeutic use of temporary p53 inhibitors in the treatment of p53-mediated diseases, conditions, and injuries is disclosed.