N-Methylglucamine acetylsalicylate | 63058-04-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-Methylglucamine acetylsalicylate
• 英文别名: 2-acetyloxybenzoic acid;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
• CAS: 63058-04-8
• 化学式: C16H25NO9
• 分子量: 375.37
• InChiKey: ZHMUKSRUNDCCLM-WZTVWXICSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.05
• 重原子数：
  26
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  177
• 氢给体数：
  7
• 氢受体数：
  10

文献信息

• US4748174A
  申请人：——

  公开号：US4748174A

  公开（公告）日：1988-05-31
• [EN] COMPOSITIONS AND PRECONCENTRATES COMPRISING AT LEAST ONE SALICYLATE AND OMEGA-3 FATTY ACID OIL MIXTURE<br/>[FR] COMPOSITIONS ET PRÉCONCENTRÉS COMPRENANT AU MOINS UN SALICYLATE ET UN MÉLANGE HUILEUX D'ACIDE GRAS OMÉGA-3
  申请人：PRONOVA BIOPHARMA NORGE AS

  公开号：WO2013072767A1

  公开（公告）日：2013-05-23

  The present disclosure relates generally to compositions and preconcentrates comprising: a fatty acid oil mixture comprising at least 70% eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) or from about 25% to about 70% EPA and DHA, by weight of the fatty acid oil mixture, wherein the EPA and DHA are in a form chosen from free fatty acid, ethyl ester, and triglyceride; and at least one salicylate. The present disclosure also relates to preconcentrates of the present disclosure in a form of a self-nanoemulsifying drug delivery system (SNEDDS), a self-microemulsifying drug delivery system (SMEDDS), or a self-emulsifying drug delivery system (SEDDS).