(2S,3S,4R)-N-ethyl-3,4,5-trihydroxyoxolane-2-carboxamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3S,4R)-N-ethyl-3,4,5-trihydroxyoxolane-2-carboxamide
• 化学式: C₇H₁₃NO₅
• 分子量: 191.18
• InChiKey: PDDKLOVJJFBKII-JHPPHWPESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  99
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• NEW MARKER FOR THE CLASSIFICATION, DIAGNOSIS AND TREATMENT OF SCOLIOSIS
  申请人：Chu Sainte-Justine

  公开号：EP3044321A1

  公开（公告）日：2016-07-20
• [EN] NEW MARKER FOR THE CLASSIFICATION, DIAGNOSIS AND TREATMENT OF SCOLIOSIS<br/>[FR] NOUVEAU MARQUEUR POUR LA CLASSIFICATION, LE DIAGNOSTIC ET LE TRAITEMENT DE LA SCOLIOSE
  申请人：CHU SAINTE JUSTINE

  公开号：WO2015032005A1

  公开（公告）日：2015-03-12

  A method of classifying a subject having idiopathic scoliosis (IS) or at risk of developing IS comprising: determining the cellular response to Gi stimulation in a cell sample from the subject in the presence of OPN; determining the cellular response to Gi stimulation in a cell sample from the subject in the absence of OPN; and comparing the cellular response obtained in the presence of OPN with the cellular response obtained in the absence of OPN, whereby the comparing step enables the classification of the subject into one IS functional group. Also provided is the use of the foregoing method to classify borderline subjects and kits for applying the methods.