5-Methyl-3-propoxy-1,2-oxazole

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-Methyl-3-propoxy-1,2-oxazole
• 英文别名: 5-methyl-3-propoxy-1,2-oxazole
• 化学式: C₇H₁₁NO₂
• 分子量: 141.17
• InChiKey: TUGLKAHXLOJGRA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  35.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• CONDENSED RING COMPOUNDS HAVING DOPAMINE D3 RECEPTOR ANTAGONISTIC EFFECT
  申请人：Shionogi & Co., Ltd.

  公开号：US20210040117A1

  公开（公告）日：2021-02-11

  Novel compounds having a D3 receptor antagonistic effect are provided. The compound represented by Formula (IA)′: wherein A is S or O; R 1a is substituted or unsubstituted alkyloxy or the like, R 2a to R 2d are each independently hydrogen atoms or the like, ring B is a 4- to 8-membered non-aromatic carbocycle or the like, R 3 is each independently halogen or the like, r is an integer of 0 to 4, R 4 is substituted or unsubstituted aromatic heterocyclyl or the like, or a pharmaceutically acceptable salt thereof.