6-氨基己烷酰肼 | 20248-37-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 6-氨基己烷酰肼
• 英文名称: 6-Aminohexanohydrazid
• 英文别名: 6-amino-hexanoic acid hydrazide；6-Amino-hexansaeure-hydrazid；6-Aminohexanehydrazide
• CAS: 20248-37-7
• 化学式: C₆H₁₅N₃O
• 分子量: 145.205
• InChiKey: ODWYSEVREAVUNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  81.1
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  6-氨基己烷酰肼 、 4-溴苯乙酮 生成 6-amino-hexanoic acid-[1-(4-bromo-phenyl)-ethylidenehydrazide]
  参考文献：
  名称：

  Adamek et al., Collection of Czechoslovak Chemical Communications, 1958, vol. 23, p. 155

  摘要：

  DOI：
• 作为产物：
  描述：

  6-氨基己酸乙酯 在 一水合肼 作用下， 生成 6-氨基己烷酰肼
  参考文献：
  名称：

  Grabenko,A.D. et al., Journal of Organic Chemistry USSR (English Translation), 1971, vol. 7, p. 2440 - 2442

  摘要：

  DOI：

文献信息

• [EN] COMPOUNDS CONTAINING MATRIX METALLOPROTEINASE SUBSTRATES AND METHODS OF THEIR USE<br/>[FR] COMPOSES CONTENANT DES SUBSTRATS DE METALLOPROTEINASE MATRICIELLE ET PROCEDES D'UTILISATION ASSOCIES
  申请人：BRISTOL MYERS SQUIBB CO

  公开号：WO2005023314A1

  公开（公告）日：2005-03-17

  Compounds for use in a diagnostic agent for detecting, imaging, and/or monitoring a pathological disorder associated with matrix metalloproteinase activity at a site of interest in a patient are disclosed. Compositions and kits containing the compounds are also disclosed. In addition, methods of detecting, imaging, and/or monitoring the presence of matrix metalloproteinase or a pathological disorder associated with matrix metalloproteinase activity in a patient are disclosed.

  揭示了用于诊断剂的化合物，用于检测、成像和/或监测患者感兴趣部位处与基质金属蛋白酶活性相关的病理紊乱。还揭示了含有这些化合物的组合物和试剂盒。此外，还揭示了检测、成像和/或监测患者体内基质金属蛋白酶或与基质金属蛋白酶活性相关的病理紊乱存在的方法。
• Compounds containing matrix metalloproteinase substrates and methods of their use
  申请人：Harris D. Thomas

  公开号：US20050106100A1

  公开（公告）日：2005-05-19

  Compounds for use in a diagnostic agent for detecting, imaging, and/or monitoring a pathological disorder associated with matrix metalloproteinase activity at a site of interest in a patient are disclosed. Compositions and kits containing the compounds are also disclosed. In addition, methods of detecting, imaging, and/or monitoring the presence of matrix metalloproteinase or a pathological disorder associated with matrix metalloprotainase activity in a patient are disclosed.

  本文介绍了用于诊断检测、成像和/或监测患者体内与基质金属蛋白酶活性相关的病理性疾病的化合物。还公开了含有这些化合物的组合物和试剂盒。此外，还公开了检测、成像和/或监测患者体内基质金属蛋白酶或与基质金属蛋白酶活性相关的病理性疾病存在的方法。
• Crosslinked compounds and methods of making and using thereof
  申请人：Prestwich D. Glenn

  公开号：US20050176620A1

  公开（公告）日：2005-08-11

  Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) the oxidative coupling of two or more thiol compounds or (2) by the reaction between at least one tbiol compound with at least one thiol-reactive compound.

  本文介绍了许多治疗中有用的交联化合物。本文介绍了两种制备交联化合物的方法：(1)通过氧化耦合两个或更多的巯基化合物或(2)通过至少一种巯基化合物与至少一种巯基反应性化合物的反应。
• Non-aqueous poly(urethane-urea)
  申请人：PPG INDUSTRIES, INC.

  公开号：EP0205829A1

  公开（公告）日：1986-12-30

  Disclosed herein is a poly(urethane-urea) which is prepared by reverse-addition of an isocyanate-terminated prepolymer to an organic medium containing an alcoholic solvent and a chain extender comprising at least two isocyanate-reactive active hydrogen groups consisting essentially of amino groups.

  本发明公开了一种聚脲烷-脲，其制备方法是将异氰酸酯封端预聚物反向添加到有机介质中，有机介质中含有醇溶剂和扩链剂，扩链剂中含有至少两个异氰酸酯反应活性氢基，这些氢基主要由氨基组成。
• Hot melt adhesive composition for bonding a locator pin to glass
  申请人：3M Innovative Properties Company

  公开号：EP1120450A1

  公开（公告）日：2001-08-01

  The present invention provides an adhesive composition comprising a uniform mixture of components, the components comprising a first and a second thermoplastic polyurethane, the first thermoplastic polyurethane being a thermoplastic polyurethane of which the shear tan δ versus temperature curve approaches infinity at a temperature above 150°C and that has a glass transition temperature of not more than 10°C, the second thermoplastic polyurethane having a softening point of not more than 80°C and the adhesive composition being solid at a temperature of 20°C and being capable of bonding to glass or a ceramic frit layer provided on glass at a temperature between 100°C and 160°C. The present invention further provides a method for bonding a locator pin to a window glass using the adhesive composition and further a locator pin having the adhesive composition.

  本发明提供了一种由均匀混合物组成的粘合剂组合物，其组分包括第一种和第二种热塑性聚氨酯，第一种热塑性聚氨酯是一种热塑性聚氨酯，其剪切力tanδ与温度的关系曲线在温度高于150℃时接近无穷大，其玻璃化温度不超过10℃、第二种热塑性聚氨酯的软化点不超过 80°C，粘合剂组合物在 20°C 的温度下为固态，能够在 100°C 至 160°C 的温度下与玻璃或玻璃上的陶瓷熔块层粘合。本发明进一步提供了一种使用该粘合剂组合物将定位销粘合到窗玻璃上的方法，并进一步提供了一种具有该粘合剂组合物的定位销。