3-Phenylmethoxy-5-propan-2-ylpyridine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Phenylmethoxy-5-propan-2-ylpyridine
• 英文别名: 3-phenylmethoxy-5-propan-2-ylpyridine
• 化学式: C₁₅H₁₇NO
• 分子量: 227.3
• InChiKey: WPGXTAAIBRMIJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] ACLY INHIBITORS AND USES THEREOF<br/>[FR] INHIBITEURS D'ACYLE ET LEURS UTILISATIONS
  申请人：NIMBUS ARTEMIS INC

  公开号：WO2020102616A1

  公开（公告）日：2020-05-22

  The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

  本发明提供了作为ATP柠檬酸裂解酶（ACLY）抑制剂的化合物，以及其组合物和使用方法。
• Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof
  申请人：PHARMAKEA, INC.

  公开号：US10588900B2

  公开（公告）日：2020-03-17

  Described herein are compounds that are LOXL2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with LOXL2 activity.

  本文描述了作为 LOXL2 抑制剂的化合物、制造此类化合物的方法、包含此类化合物的药物组合物和药物，以及使用此类化合物治疗与 LOXL2 活性相关的病症、疾病或失调的方法。
• QUINOLINONE LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF
  申请人：PHARMAKEA, INC.

  公开号：US20190046520A1

  公开（公告）日：2019-02-14

  Described herein are compounds that are LOXL2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with LOXL2 activity.
• ACLY INHIBITORS AND USES THEREOF
  申请人：Nimbus Artemis, Inc.

  公开号：US20200157076A1

  公开（公告）日：2020-05-21

  The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.