(3R,4S,6R)-2-[[(2R,4R,5S)-3-methyl-4,5-bis(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]oxymethyl]-6-[(2R,4S,5R)-2-methylsulfanyl-4,5-bis(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-3-yl]oxy-3,4,5-tris(phenylmethoxy)oxane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3R,4S,6R)-2-[[(2R,4R,5S)-3-methyl-4,5-bis(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]oxymethyl]-6-[(2R,4S,5R)-2-methylsulfanyl-4,5-bis(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-3-yl]oxy-3,4,5-tris(phenylmethoxy)oxane
• 化学式: C₈₃H₉₀O₁₄S
• 分子量: 1343.7
• InChiKey: GXYXHYTVZUMSSD-AJVZGDNRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.6
• 重原子数：
  98
• 可旋转键数：
  35
• 环数：
  12.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  155
• 氢给体数：
  0
• 氢受体数：
  15

文献信息

• Method of preparing a sugar chain library and use thereof
  申请人：Matsuo Ichiro

  公开号：US20070254344A1

  公开（公告）日：2007-11-01

  The present invention provides methods which enables synthesis of various sugar chains and products obtained by the same. More specifically, the present invention provides protected sugar chain compounds represented by the formula (I) below: [wherein R 1 and R 2 are the same or different and each is a linear or branched sugar chain, S 1 is any sugar residue, S A and S B are the same or different sugar residues, L is a bond or a linear sugar chain, X is absent, or, if present, represents certain group, the sugar residues S A and S B are cleaved by different exoglycosidases, respectively] and libraries thereof, and methods of producing the same; methods of producing a sugar chain compound, which comprises treating the sugar chain compound or library with glycosidase, and glycosidase decomposition products obtained by the same; intermediates for the synthesis of protected sugar chain compounds; reagents and kits; and the like.

  本发明提供了各种糖链的合成方法以及由此获得的产品。更具体地，本发明提供了由下式(I)表示的受保护的糖链化合物：[其中，R1和R2相同或不同，每个都是线性或支链糖链，S1是任何糖残基，SA和SB是相同或不同的糖残基，L是键或线性糖链，X不存在，或者如果存在，则代表某些基团，糖残基SA和SB分别通过不同的外切糖基酶裂解]及其文库，以及其制备方法；制备糖链化合物的方法，包括处理糖链化合物或文库与酶解糖苷酶的方法，以及由此获得的酶解糖苷酶分解产物；受保护的糖链化合物合成的中间体；试剂和试剂盒等。
• US7879766B2
  申请人：——

  公开号：US7879766B2

  公开（公告）日：2011-02-01