4-Ethyl-2,6-dimethoxypyridine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-Ethyl-2,6-dimethoxypyridine
• 英文别名: 4-ethyl-2,6-dimethoxypyridine
• 化学式: C₉H₁₃NO₂
• 分子量: 167.2
• InChiKey: FSUIFAHLPJSYTM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  31.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] PESTICIDAL COMPOUNDS<br/>[FR] COMPOSÉS PESTICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2016012333A1

  公开（公告）日：2016-01-28

  A method of combating and controlling insects, acarines, nematodes or molluscs which comprises applying to a pest, to a locus of a pest, or to a plant susceptible to attack by a pest an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula (I), wherein R1 is R4, YR5 or ZR6; Y is CO or C=S; Z is S, S(O), SO2 or PO2; and A is an optionally substituted phenyl or an optionally substituted heteroaromatic ring, wherein R1 to R6 are defined organic groups; new compounds are also provided.

  一种用于对抗和控制昆虫、螨虫、线虫或软体动物的方法，包括向害虫、害虫栖息地或易受害虫攻击的植物施加化学式(I)中的一种化合物的杀虫、杀螨、杀线虫或杀软体动物有效量，其中R1为R4、YR5或ZR6；Y为CO或C=S；Z为S、S(O)、SO2或PO2；A为一个可选择取代的苯基或可选择取代的杂环，其中R1至R6为定义的有机基团；还提供了新的化合物。
• 2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2H)-one compounds as inhibitors of FGFR tyrosine kinases
  申请人：Array BioPharma Inc.

  公开号：US10766881B2

  公开（公告）日：2020-09-08

  Provided herein are compounds of the general Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which X, R1, R2, R3, Ring A and z have the meanings given in the specification, which are inhibitors of FGFR1, FGFR2, FGFR3 and/or FGFR4 and are useful in the treatment and prevention of diseases which can be treated with an FGFR inhibitor, including diseases or disorders mediated by FGFR1, FGFR2, FGFR3 and/or FGFR4.

  本文提供的是通式 I 的化合物： 及其立体异构体和药学上可接受的盐或溶液，其中 X、R1、R2、R3、环 A 和 z 具有说明书中给出的含义，它们是 FGFR1、FGFR2、FGFR3 和/或 FGFR4 的抑制剂，可用于治疗和预防可用 FGFR 抑制剂治疗的疾病，包括由 FGFR1、FGFR2、FGFR3 和/或 FGFR4 介导的疾病或紊乱。
• 2-ARYL- AND 2-HETEROARYL-SUBSTITUTED 2-PYRIDAZIN-3(2H)-ONE COMPOUNDS AS INHIBITORS OF FGFR TYROSINE KINASES
  申请人：Array BioPharma Inc.

  公开号：US20190300511A1

  公开（公告）日：2019-10-03

  Provided herein are compounds of the general Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which X, R 1 , R 2 , R 3 , Ring A and z have the meanings given in the specification, which are inhibitors of FGFR1, FGFR2, FGFR3 and/or FGFR4 and are useful in the treatment and prevention of diseases which can be treated with an FGFR inhibitor, including diseases or disorders mediated by FGFR1, FGFR2, FGFR3 and/or FGFR4.
• WO2022272060A1
  申请人：——

  公开号：WO2022272060A1

  公开（公告）日：2022-12-29