N-methyloleamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-methyloleamide
• 英文别名: N-methyloctadec-9-enamide
• 化学式: C₁₉H₃₇NO
• 分子量: 295.509
• InChiKey: NJNFUPWMCKHLRE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  21
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-methyloleamide 在 甲醇 、 甲酸 、 六氟异丙醇 、 palladium 10% on activated carbon 、 potassium formate 作用下， 以 四氢呋喃 、 1,2-二氯乙烷 为溶剂， 反应 72.0h， 生成 9,10-dihydroxy-N-methyloctadecanamide
  参考文献：
  名称：

  以硝基芳烃为光敏氧化剂的烯烃二羟基化反应

  摘要：

  光激发的硝基芳烃可与 Pd 介导的氢化结合使用，作为烯烃二羟基化的锇替代物。

  DOI：

  10.1002/anie.202214508

文献信息

• PROCESS FOR ALKENYLATING CARBOXAMIDES
  申请人：Staffel Wolfgang

  公开号：US20090131657A1

  公开（公告）日：2009-05-21

  The present invention relates to a process for preparing N-(1-alkenyl)carboxamides of the formula I, which comprises reacting a carboxamide of the formula II with an alkyne of the formula III in the presence of a catalyst selected from among carbonyl complexes, halides and oxides of rhenium, manganese, tungsten, molybdenum, chromium and iron.

  本发明涉及一种制备式I的N-(1-烯基)羧酰胺的方法，包括在选择自铼、锰、钨、钼、铬和铁的羰基配合物、卤化物和氧化物之一作为催化剂的情况下，将式II的羧酰胺与式III的炔烃反应。
• A METHOD OF TREATING PERIPHERAL INFLAMMATORY DISEASE
  申请人：Dublin City University

  公开号：EP3095444A1

  公开（公告）日：2016-11-23

  An active for use in the treatment or inhibition of an inflammatory disease associated with over-activation of Toll-like Receptor 4 (TLR4), Toll-like Receptor 2 (TLR2) and Myeloid differentiating protein 88 (Myd88) adaptor-like protein (Mal) while maintaining a subject's ability to respond normally to a pathogen, in which the active is an oleamide or a derivative thereof.

  一种用于治疗或抑制与Toll样受体4（TLR4）、Toll样受体2（TLR2）和髓样分化蛋白88（Myd88）适配样蛋白（Mal）过度激活相关的炎症性疾病，并同时保持受试者对病原体正常反应能力的活性物质为油酰胺或其衍生物。
• Friction reducing additives and compositions thereof
  申请人：MOBIL OIL CORPORATION

  公开号：EP0032415A2

  公开（公告）日：1981-07-22

  Alkyl amines, alkyl diamines and borated adducts of alkyl amines and diamines are effective friction reducing additives when incorporated into lubricating oils.

  烷基胺、烷基二胺以及烷基胺和二胺的硼化加合物加入润滑油后，可有效减少摩擦。
• Mouldable composition
  申请人：SANYO CHEMICAL INDUSTRIES LTD.

  公开号：EP0329475A2

  公开（公告）日：1989-08-23

  Mouldable compositions comprising a metallic powder or a combination thereof with ceramic powder, mixed with an organic binder are disclosed, at least a part of which binder comprises a synthetic resin component (A) having a heat deformation temperature of 130°C or higher. The component A may be used in combination with another component (B) having a melting point of 30°C - 100°C, with or without another thermoplastic component (C), having a heat deformation temperature of 130°C or less. Mouldable compositions, comprising metallic and/or ceramic powder mixed with an organic binder comprising a secondary or tertiary amine (D), or a combination thereof with a thermoplastic resin (E), are also disclosed.

  本发明公开了由金属粉末或其与陶瓷粉末的组合与有机粘合剂混合而成的可模塑组合物，其中至少一部分粘合剂包括热变形温度为 130°C 或更高的合成树脂成分（A）。成分 A 可与另一种熔点为 30°C - 100°C 的成分 (B) 结合使用，也可与另一种热塑性成分 (C) 结合使用，后者的热变形温度为 130°C 或更低。此外，还公开了由金属和/或陶瓷粉末与有机粘合剂（包括仲胺或叔胺）（D）或其与热塑性树脂（E）的组合物）混合而成的可模塑组合物。
• Rubber composition containing silica or silicate and salt of an amine
  申请人：BRIDGESTONE CORPORATION

  公开号：EP1081187A2

  公开（公告）日：2001-03-07

  A rubber composition which comprises (A) at least one rubber component selected from the group consisting of natural rubber and diene synthetic rubbers, (B) an inorganic filler comprising at least one filler selected from silica and silicates as the main component and (C) an addition salt of an amine represented by general formula (I): wherein R1 represents a C8 to C24 alkyl group, an aryl group or an aralkyl group, R2 and R3 represent a hydrogen atom, a C1 to C12 alkyl group, an aryl group, an aralkyl group or a hydroxyalkyl group and R4 represents a C6 to C24 alkyl or alkenyl group, an aryl group or an aralkyl group; and a pneumatic tire produced by using the rubber composition. Fuel consumption of a pneumatic tire is decreased and workability and productivity in vulcanization in the production of a pneumatic tire are improved by using the rubber composition.

  一种橡胶组合物，包括(A)至少一种选自天然橡胶和二烯合成橡胶的橡胶组分，(B)至少一种选自二氧化硅和硅酸盐的无机填料作为主要组分，以及(C)通式(I)代表的胺的加成盐： 其中 R1 代表 C8 至 C24 烷基、芳基或芳烷基，R2 和 R3 代表氢原子、C1 至 C12 烷基、芳基、芳烷基或羟烷基，R4 代表 C6 至 C24 烷基或烯基、芳基或芳烷基；以及使用该橡胶组合物生产的充气轮胎。 使用该橡胶组合物可降低充气轮胎的燃料消耗，提高生产充气轮胎时硫化的作业性和生产率。