N-[2-[2-(2-aminoethoxy)propan-2-yloxy]ethyl]acetamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-[2-[2-(2-aminoethoxy)propan-2-yloxy]ethyl]acetamide
• 化学式: C₉H₂₀N₂O₃
• 分子量: 204.27
• InChiKey: MRAPLWNGRKLATQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  73.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY
  申请人：Sixfold Bioscience Ltd.

  公开号：US20210330810A1

  公开（公告）日：2021-10-28

  The invention provides compositions containing cargo molecules attached to elements that improve the function of the cargo molecules in the body of a subject. The compositions are useful for therapeutic and diagnostic purposes. Furthermore, the invention outlines ways in which these compositions can be produced; the core molecule can be functionalized, via bioorthogonal click chemistry, in such a way as to impart modular characteristics. This functionalization simultaneously allows for loading of biologically relevant cargo and provides stabilization to the overall structure of the molecule.

  本发明提供了一种包含附着于能够改善受试者体内载荷分子功能的元素的组合物。该组合物在治疗和诊断方面具有用途。此外，本发明还概述了可生产这些组合物的方法；核心分子可以通过生物正交点击化学功能化，以赋予模块化特性。这种功能化同时允许装载生物相关载荷并为分子的整体结构提供稳定性。
• Compositions containing nucleic acid nanoparticles with modular functionality
  申请人：Sixfold Bioscience Ltd.

  公开号：US11357865B2

  公开（公告）日：2022-06-14

  The invention provides compositions containing cargo molecules attached to elements that improve the function of the cargo molecules in the body of a subject. The compositions are useful for therapeutic and diagnostic purposes. Furthermore, the invention outlines ways in which these compositions can be produced; the core molecule can be functionalized, via bioorthogonal click chemistry, in such a way as to impart modular characteristics. This functionalization simultaneously allows for loading of biologically relevant cargo and provides stabilization to the overall structure of the molecule.

  本发明提供了含有附着在元件上的货物分子的组合物，这些元件可改善货物分子在受试者体内的功能。这些组合物可用于治疗和诊断目的。此外，本发明还概述了生产这些组合物的方法；核心分子可通过生物正交点击化学进行功能化，从而赋予模块化特性。这种功能化同时允许装载生物相关的货物，并为分子的整体结构提供稳定性。
• COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS
  申请人：Sixfold Bioscience Ltd.

  公开号：EP4022058A2

  公开（公告）日：2022-07-06