[(3R)-1-[[(2R,3R,4S,5R)-6-[(2R,3R,4R,5S,6R)-3-[[(3R)-3-dodecanoyloxytetradecanoyl]amino]-6-(hydroxymethyl)-5-phosphonooxy-4-[(3R)-3-tetradecanoyloxytetradecanoyl]oxyoxan-2-yl]oxy-3,4,5-trihydroxy-1-oxohexan-2-yl]amino]-1-oxotetradecan-3-yl] hexadecanoate | 143110-73-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(3R)-1-[[(2R,3R,4S,5R)-6-[(2R,3R,4R,5S,6R)-3-[[(3R)-3-dodecanoyloxytetradecanoyl]amino]-6-(hydroxymethyl)-5-phosphonooxy-4-[(3R)-3-tetradecanoyloxytetradecanoyl]oxyoxan-2-yl]oxy-3,4,5-trihydroxy-1-oxohexan-2-yl]amino]-1-oxotetradecan-3-yl] hexadecanoate
• CAS: 143110-73-0
• 化学式: C₉₆H₁₈₁N₂O₂₁P
• 分子量: 1730.4
• InChiKey: JDEGQXOBEAJRSW-QXFLKPNTSA-N

物化性质

• 密度：
  1.08±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  29.1
• 重原子数：
  120
• 可旋转键数：
  92
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  347
• 氢给体数：
  8
• 氢受体数：
  21

文献信息

• DRY PHARMACEUTICAL COMPOSITION FOR INHALATION
  申请人：Deutsches Krebsforschungszentrum

  公开号：US20210338575A1

  公开（公告）日：2021-11-04

  The present invention relates to a dry pharmaceutical composition for inhalation comprising an antigen and an amphiphilic immune stimulant, wherein said pharmaceutical composition was produced by spray-drying; and to a dry pharmaceutical composition obtained or obtainable by spray-drying a solution comprising an antigen, an amphiphilic immune stimulant, and, optionally, a bulking agent. The present invention also relates to said dry pharmaceutical composition for use in medicine, in particular for use in vaccination of a subject; and to methods and kits related thereto.
• [EN] DRY PHARMACEUTICAL COMPOSITION FOR INHALATION<br/>[FR] COMPOSITION PHARMACEUTIQUE SÈCHE À INHALER
  申请人：DEUTSCHES KREBSFORSCH

  公开号：WO2020079185A1

  公开（公告）日：2020-04-23

  The present invention relates to a dry pharmaceutical composition for inhalation comprising an antigen and an amphiphilic immune stimulant, wherein said pharmaceutical composition was produced by spray-drying; and to a dry pharmaceutical composition obtained or obtainable by spray-drying a solution comprising an antigen, an amphiphilic immune stimulant, and, optionally, a bulking agent. The present invention also relates to said dry pharmaceutical composition for use in medicine, in particular for use in vaccination of a subject; and to methods and kits related thereto.