N-[(2R,4R,5S)-5-[(2S,4S,5S)-3-amino-4-hydroxy-6-(hydroxymethyl)-5-methyloxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)-2-methoxyoxan-3-yl]acetamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-[(2R,4R,5S)-5-[(2S,4S,5S)-3-amino-4-hydroxy-6-(hydroxymethyl)-5-methyloxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)-2-methoxyoxan-3-yl]acetamide
• 化学式: C₁₆H₃₀N₂O₉
• 分子量: 394.42
• InChiKey: PIGLAZYOJHKABV-IQKDTOCESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.6
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  173
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• WATER SOLUBLE NITRIC OXIDE-RELEASING POLYGLUCOSAMINES AND USES THEREOF
  申请人：The University of North Carolina at Chapel Hill

  公开号：US20150225488A1

  公开（公告）日：2015-08-13

  The presently disclosed subject matter provides nitric oxide-releasing polysaccharides and oligosaccharides, in particular, polyglucosamines, and their use in biomedical and pharmaceutical applications. More particularly, in some embodiments, the presently disclosed subject matter provides nitric oxide-releasing polysaccharides and oligosaccharides that release nitric oxide in a controlled and targeted manner, thereby prolonging the therapeutic effects of nitric oxide and improving the specificity of nitric oxide delivery to targeted cells and/or tissues.
• US9850322B2
  申请人：——

  公开号：US9850322B2

  公开（公告）日：2017-12-26