Trehalose 2-sulfate | 141923-45-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Trehalose 2-sulfate
• 英文别名: [(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-3-yl] hydrogen sulfate
• CAS: 141923-45-7
• 化学式: C₁₂H₂₂O₁₄S
• 分子量: 422.36
• InChiKey: WVFKPISWLUJJIJ-LIZSDCNHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.6
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  241
• 氢给体数：
  8
• 氢受体数：
  14

文献信息

• EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME
  申请人：HAYASHIBARA CO., LTD.

  公开号：US20150342854A1

  公开（公告）日：2015-12-03

  The present invention has an object to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as wrinkles, fine wrinkles, blemishes, and saggings caused by increasing age or ageing; and maintains or improves the barrier function and the hyaluronic acid production in the skin. The object is solved by providing an external dermal composition for anti-ageing, which contains an aqueous medium as a base material and one or more ingredients selected from L-ascorbic acid, derivatives thereof, and their salts as an effective ingredient(s).

  本发明的目的是提供一种用于抗衰老的外用皮肤组成物，该组成物可以预防或改善因年龄增长或衰老引起的皮肤问题，如皱纹、细纹、斑点和下垂，并维持或改善皮肤的屏障功能和透明质酸的产生。本发明通过提供一种外用皮肤组成物来实现该目的，该组成物包含水性介质作为基材料，并含有一种或多种从L-抗坏血酸、其衍生物和它们的盐中选择的成分作为有效成分。
• Process for producing trehalose derivatives
  申请人：KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO

  公开号：EP0714905A2

  公开（公告）日：1996-06-05

  High quality trehalose derivatives are readily prepared in a considerably high yield by reacting anhydrous trehalose with reactive reagents under anhydrous conditions. The trehalose derivatives can be used in a variety of fields in the production, the chemical synthesis, and the enzymatic synthesis of foods, cosmetics, pharmaceuticals, detergents and chemicals as surfactants, humectants, skin-beautifying agents, antitumor agents, and intermediates for chemical and enzymatic syntheses.

  在无水条件下，无水曲哈糖与活性试剂发生反应，很容易制备出产率相当高的高品质曲哈糖衍生物。这些曲哈洛糖衍生物可作为表面活性剂、保湿剂、美肤剂、抗肿瘤剂以及化学合成和酶合成的中间体，用于食品、化妆品、药品、清洁剂和化学品的生产、化学合成和酶合成等多个领域。
• REMEDIES
  申请人：Takara Shuzo Co, Ltd.

  公开号：EP1175907A1

  公开（公告）日：2002-01-30

  The present invention provides a therapeutic agent or prophylactic agent for a disease requiring induction of growth factor production, a food, beverage or feed for induction of growth factor production, a cosmetic for induction of growth factor production, and a controlling agent for growth factor production, characterized in that each comprises as an effective ingredient a compound selected from the group consisting of acidic polysaccharides, degradation products thereof, acidic oligosaccharides, acidic monosaccharides, acidic sugar alcohols and salts thereof, wherein the compound has induction action for growth factor production.

  本发明提供了一种用于需要诱导生长因子产生的疾病的治疗剂或预防剂，一种用于诱导生长因子产生的食品、饮料或饲料，一种用于诱导生长因子产生的化妆品，以及一种用于生长因子产生的控制剂、其特征在于，每种物质都包含一种选自酸性多糖、其降解产物、酸性寡糖、酸性单糖、酸性糖醇及其盐类的化合物作为有效成分，其中该化合物具有诱导生长因子产生的作用。
• METHOD AND REAGENT FOR MEASURING CHOLESTEROL IN HIGH DENSITY LIPOPROTEINS
  申请人：Kyowa Medex Co., Ltd.

  公开号：EP1555326A1

  公开（公告）日：2005-07-20

  A method for quantitatively determining cholesterol in high-density lipoprotein in a sample, which comprises: reacting a sample with i) cholesterol esterase and cholesterol oxidase or ii) cholesterol esterase, an oxidized coenzyme and cholesterol dehydrogenase in an aqueous medium comprising i) nonionic surfactant, polyanion and albumin or ii) a combination of a surfactant selected from the group consisting of polyoxyethylene alkylamine or polyoxyethylene alkenylamine and a surfactant selected from the group consisting of polyoxyethylene polycyclic phenyl ether sulfate and an anionic bile acid derivative, and measuring the formed hydrogen peroxide or a reduced coenzyme; and a reagent used therefor.

  一种定量测定样品中高密度脂蛋白胆固醇含量的方法，包括将样品与 i）胆固醇酯酶和胆固醇氧化酶或 ii）胆固醇酯酶、氧化辅酶和胆固醇脱氢酶在水介质中反应，该水介质包括 i）非离子表面活性剂、聚阴离子和白蛋白，或 ii) 选自聚氧乙烯烷基胺或聚氧乙烯烯基胺和选自聚氧乙烯多环苯基醚硫酸盐和阴离子胆汁酸衍生物组的表面活性剂的组合，并测量形成的过氧化氢或还原辅酶；以及用于此目的的试剂。
• METHOD FOR DETERMINATION OF CHOLESTEROL IN HIGH-DENSITY LIPOPROTEIN
  申请人：KYOWA MEDEX CO., LTD.

  公开号：EP1876243A1

  公开（公告）日：2008-01-09

  The present invention provides a reagent, a reagent and a kit for the simple and accurate measurement of HDL cholesterol. The method for the measurement of cholesterol in high-density lipoprotein in a sample comprises reacting the sample with i) cholesterol esterase and cholesterol oxidase or ii) cholesterol esterase, oxidized coenzyme and cholesterol dehydrogenase in an aqueous medium comprising a specific nitrogen-containing surfactant having the structure of amine or ammonium salt and a polyanion, and measuring the formed hydrogen peroxide or reduced coenzyme.

  本发明提供一种试剂、一种试剂和一种试剂盒，用于简单准确地测量高密度脂蛋白胆固醇。测量样品中高密度脂蛋白胆固醇的方法包括：在含有特定含氮表面活性剂（其结构为胺或铵盐和聚阴离子）的水介质中，使样品与 i) 胆固醇酯酶和胆固醇氧化酶或 ii) 胆固醇酯酶、氧化辅酶和胆固醇脱氢酶反应，并测量形成的过氧化氢或还原辅酶。