6-(Hydroxymethyl)-5-methyl-2-propoxyoxane-3,4-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-(Hydroxymethyl)-5-methyl-2-propoxyoxane-3,4-diol
• 英文别名: 6-(hydroxymethyl)-5-methyl-2-propoxyoxane-3,4-diol
• 化学式: C₁₀H₂₀O₅
• 分子量: 220.26
• InChiKey: ZSFIGKFPZBPPNN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  79.2
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• COMPOSITIONS AND METHODS TO IMPROVE THE THERAPEUTIC BENEFIT OF INDIRUBIN AND ANALOGS THEREOF, INCLUDING MEISOINDIGO
  申请人：BROWN Dennis

  公开号：US20150087687A1

  公开（公告）日：2015-03-26

  The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutically active agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to therapeutically active agents selected from the group consisting of: (i) indirubin; (ii) an analog of indirubin; (iii) a derivative of indirubin or of an analog of indirubin; and (iv) a pharmaceutical composition comprising indirubin, an analog of indirubin, or a derivative of indirubin or of an analog of indirubin, especially meisoindigo.