1-ethyl-2,3-methylimidazolium methyl sulfate | 885456-19-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-ethyl-2,3-methylimidazolium methyl sulfate
• 英文别名: 1-ethyl-2,3-dimethylimidazolium methylsulfate；1-Ethyl-2,3-dimethylimidazol-3-ium;methyl sulfate；1-ethyl-2,3-dimethylimidazol-3-ium;methyl sulfate
• CAS: 885456-19-9
• 化学式: CH₃O₄S*C₇H₁₃N₂
• 分子量: 236.292
• InChiKey: HUJPAQONNRCXCP-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.27
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  83.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-ethyl-2,3-methylimidazolium methyl sulfate 、 bis(trifluoromethane)sulfonimide lithium 以 水 为溶剂， 反应 4.0h， 以89%的产率得到1-乙基-2,3-二甲基咪唑鎓双(三氟甲磺酰)亚胺
  参考文献：
  名称：

  卤素键对离子液体中电化学阴离子氧化的影响

  摘要：

  已经比较了基于咪唑鎓核的三种离子液体 (IL)，并将其用作各种阴离子氧化的溶剂。电化学实验以及 NMR 滴定和 X 射线衍射分析明确证实了非共价卤素键对氧化电位的关键作用，因此对相应 IL 的电化学窗口。

  DOI：

  10.1039/d1ob01031j

文献信息

• Process For The Preparation Of Onium Alkylsulfates Having A Low Halide Content
  申请人：Ignatyev Nikolai

  公开号：US20100222580A1

  公开（公告）日：2010-09-02

  The invention relates to a process for the preparation of onium alkylsulfates by reaction of an onium halide with a symmetrically substituted dialkyl sulfate, in which the alkyl group can have 1 to 14 C atoms, with an asymmetrically substituted dialkyl sulfate, in which one alkyl group can have 4 to 20 C atoms and the second alkyl group denotes methyl or ethyl, with an alkyl trialkylsilyl sulfate, with an alkyl acyl sulfate or with an alkyl sulfonyl sulfate, where the reaction with a dialkyl sulfate is carried out at room temperature.

  本发明涉及一种通过将onium卤化物与对称取代的二烷基硫酸盐、其中烷基基团可以有1至14个C原子，不对称取代的二烷基硫酸盐、其中一个烷基基团可以有4至20个C原子，第二个烷基基团表示甲基或乙基，烷基三烷基硅酸盐、烷基酰基硫酸盐或烷基磺酰基硫酸盐反应制备onium烷基硫酸盐的方法，在与二烷基硫酸盐反应时在室温下进行。
• Process for the synthesis of carbamates using co2
  申请人：HUNTSMAN INTERNATIONAL LLC

  公开号：EP2011782A1

  公开（公告）日：2009-01-07

  Process for the synthesis of carbamate derivatives from amine compounds, alcohols and CO2 in the presence of ionic liquids and optionally in the presence of a base.

  在离子液体和碱的作用下，由胺化合物、醇和二氧化碳合成氨基甲酸酯衍生物的工艺。
• ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY
  申请人：CustomArray,Inc.

  公开号：EP3521485A1

  公开（公告）日：2019-08-07

  There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.

  本发明公开了一种用于电极微阵列的电化学解锁溶液。还进一步公开了一种使用该电化学解锁溶液在电极阵列上进行电化学合成的方法。该溶液和方法用于去除酸性保护基团，以便在电极微阵列上合成寡核苷酸、肽、小分子或聚合物，同时大幅提高与活性电极的解锁隔离度。该方法包括向电极阵列中的至少一个电极施加电压或电流。电极阵列被电化学解锁溶液覆盖。
• Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array
  申请人：CustomArray, Inc.

  公开号：US10006131B1

  公开（公告）日：2018-06-26

  There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.

  本发明公开了一种用于电极微阵列的电化学解锁溶液。还进一步公开了一种使用该电化学解锁溶液在电极阵列上进行电化学合成的方法。该溶液和方法用于去除酸性保护基团，以便在电极微阵列上合成寡核苷酸、肽、小分子或聚合物，同时大幅提高与活性电极的解锁隔离度。该方法包括向电极阵列中的至少一个电极施加电压或电流。电极阵列被电化学解锁溶液覆盖。
• High efficiency, small volume nucleic acid synthesis
  申请人：LIFE TECHNOLOGIES CORPORATION

  公开号：US10407676B2

  公开（公告）日：2019-09-10

  The disclosure generally relates to compositions and methods for the production of nucleic acid molecules. In some aspects, the invention allows for the microscale generation of nucleic acid molecules, optionally followed by assembly of these nucleic acid molecules into larger molecules. In some aspects, the invention allows for efficient production of nucleic acid molecules (e.g., large nucleic acid molecules such as genomes).

  本发明一般涉及生产核酸分子的组合物和方法。在某些方面，本发明可以微量生成核酸分子，然后将这些核酸分子组装成更大的分子。在某些方面，本发明可高效生产核酸分子（如基因组等大核酸分子）。