2-(4-(methylthio)phenyl)-4,5-diphenyl-1H-imidazole | 36755-90-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(4-(methylthio)phenyl)-4,5-diphenyl-1H-imidazole
• 英文别名: 2-(4-methylthiophenyl)-4,5-diphenylimidazole；2-(4-methylsulfanylphenyl)-4,5-diphenyl-1H-imidazole
• CAS: 36755-90-5
• 化学式: C₂₂H₁₈N₂S
• 分子量: 342.464
• InChiKey: GZYZPHPDKCTFFH-UHFFFAOYSA-N

物化性质

• 熔点：
  242-244 °C(Solv: acetone (67-64-1); water (7732-18-5))
• 沸点：
  555.1±38.0 °C(Predicted)
• 密度：
  1.26±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  54
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  联苯甲酰 、 4-(甲基巯基)苯甲醛 在 ammonium acetate 作用下， 反应 0.5h， 以90%的产率得到2-(4-(methylthio)phenyl)-4,5-diphenyl-1H-imidazole
  参考文献：
  名称：

  二氧化硅键合的S-磺酸：无溶剂条件下合成三取代咪唑的可回收催化剂

  摘要：

  在二氧化硅键合的S-磺酸作为催化剂的存在下，高取代度合成了三取代的咪唑。反应在无溶剂条件下于130°C进行。反应后处理很简单，催化剂很容易通过过滤从产物中分离出来。

  DOI：

  10.1002/cjoc.201090129

文献信息

• Efficient Multi-component Synthesis of Highly Substituted Imidazoles Utilizing P2O5/SiO2 as a Reusable Catalyst
  作者：Hamid Reza Shaterian、Mohammad Ranjbar、Kobra Azizi

  DOI：10.1002/cjoc.201180293

  日期：2011.8

  gel (P2O5/SiO2) has been used as an efficient and reusable catalyst for the one‐pot pseudo four‐component synthesis of 2,4,5‐trisubstituted imidazoles from benzil or benzoin, aldehydes, and ammonium acetate. It was also used for four‐component preparation of 1,2,4,5‐tetrasubstituted imidazoles from benzil or benzoin, aldehydes, primary amine, and ammonium acetate under thermal solvent‐free conditions

  负载在硅胶（P 2 O 5 / SiO 2）上的五氧化二磷已被用作一种高效且可重复使用的催化剂，用于由苯甲腈或安息香，醛，和醋酸铵。它也可在无热溶剂的条件下用于由苄基或安息香，醛，伯胺和乙酸铵四组分制备1,2,4,5-四取代的咪唑。这种新方法的显着特征是高转化率，更清洁的反应，简单的实验和后处理程序，并且催化剂可以轻松地从反应混合物中分离出来并重复使用几次，而不会损失其活性。
• Synthesis of highly substituted imidazoles using Brønsted acidic ionic liquid, triphenyl(propyl-3-sulphonyl)phosphonium toluenesulfonate, as teusable catalyst
  作者：H. R. Shaterian、M. Ranjbar、K. Azizi

  DOI：10.1007/bf03246570

  日期：2011.12

  Brønsted acidic ionic liquid, triphenyl(propyl-3-sulphonyl)phosphonium toluenesulfonate, has been used as an efficient and reusable catalyst for the one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles under solvent-free conditions in excellent yields.

  布朗斯台德酸性离子液体三苯基（丙基-3-磺酰基）phosph磺酸甲苯磺酸盐已被用作一锅合成2,4,5-三取代和1,2,4,5-四取代的咪唑的有效且可重复使用的催化剂在无溶剂条件下，收率极高。
• An environmental friendly approach for the synthesis of highly substituted imidazoles using Brønsted acidic ionic liquid, N-methyl-2-pyrrolidonium hydrogen sulfate, as reusable catalyst
  作者：Hamid Reza Shaterian、Mohammad Ranjbar

  DOI：10.1016/j.molliq.2011.02.012

  日期：2011.4

  Brønsted acidic ionic liquid, N-methyl-2-pyrrolidonium hydrogen sulfate, has been used as an efficient and reusable catalyst for the one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles under thermal solvent-free conditions in excellent yields.

  布朗斯台德酸性离子液体N-甲基-2-吡咯烷鎓硫酸氢盐已被用作一种高效且可重复使用的催化剂，用于在以下条件下一锅合成2,4,5-三取代和1,2,4,5-四取代的咪唑无溶剂的热条件，产率高。
• DICHROIC DYE FOR POLARIZATION FILM, COMPOSITION COMPRISING THE SAME FOR POLARIZATION FILM, METHOD FOR FORMING POLARIZATION PLATE AND POLARIZATION PLATE PREPARED THEREBY
  申请人：Cho Yong-Il

  公开号：US20090290214A1

  公开（公告）日：2009-11-26

  Disclosed are a new dichroic dye having liquid crystal properties and dichroic properties and capable of being used for forming a polarization film with excellent heat resistance, durability, and polarizing properties, a composition including the same for a polarization film, a method for forming a polarization plate with excellent durability using the composition, and a polarization plate prepared thereby. The new dichroic dye has a structure of R1-L1-(M,L,D) (where, D is a dichroic structure, M is a structure with liquid crystal properties, R1 is a reactive end functional group, and L and L1 are linking structures). The composition for a polarization film includes the dichroic dye. In the method for forming the polarization plate, the composition for a polarization film is applied to a substrate and cured to prepare the polarization plate. The polarization plate has excellent dichroic ratio, heat resistance, durability, and polarizing properties.

  本发明公开了一种新的具有液晶性能和双折射性能的二色染料，可用于形成具有优异耐热性、耐久性和偏振性能的偏振膜的组合物，以及使用该组合物制备具有优异耐久性的偏振板的方法和所制备的偏振板。新的二色染料具有R1-L1-(M,L,D)的结构（其中，D是双折射结构，M是具有液晶性能的结构，R1是反应性末端功能团，L和L1是连接结构）。偏振膜的组合物包括该二色染料。在制备偏振板的方法中，将偏振膜的组合物涂覆在基板上并固化以制备偏振板。该偏振板具有优异的双折射比、耐热性、耐久性和偏振性能。
• Functionalized copolymer for photopolymerizable composition
  申请人：Shipley Company, L.L.C.

  公开号：EP1429184A1

  公开（公告）日：2004-06-16

  A functionalized copolymer containing a main chain derived from polymerizable monomers and pendent functional groups terminated with one or more α or β ethylenically or acetylenically unsaturated groups. The functionalized copolymers are self cross-linking and are suitable for use as binders.

  一种官能化共聚物，含有由可聚合单体衍生的主链和以一个或多个 α 或 β 乙烯基或乙炔基不饱和基团终止的悬垂官能团。官能化共聚物具有自交联性，适合用作粘合剂。