2-(2,4-dichlorobenzyl)-4,5-diphenylimidazole | 172321-34-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(2,4-dichlorobenzyl)-4,5-diphenylimidazole
• 英文别名: 2-[(2,4-dichlorophenyl)methyl]-4,5-diphenyl-1H-imidazole
• CAS: 172321-34-5
• 化学式: C₂₂H₁₆Cl₂N₂
• 分子量: 379.288
• InChiKey: AWVKQWIOURZHQZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  28.7
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (2,4-二氯苯基)乙醛 、 安息香精油 在 triphenyl(propyl-3-sulphonyl)phosphonium toluenesulfonate 、 ammonium acetate 作用下， 反应 1.5h， 以98%的产率得到2-(2,4-dichlorobenzyl)-4,5-diphenylimidazole
  参考文献：
  名称：

  使用布朗斯台德酸性离子液体，甲苯磺酸三苯基（丙基-3-磺酰基）phosph磺酸酯合成高度取代的咪唑

  摘要：

  布朗斯台德酸性离子液体三苯基（丙基-3-磺酰基）phosph磺酸甲苯磺酸盐已被用作一锅合成2,4,5-三取代和1,2,4,5-四取代的咪唑的有效且可重复使用的催化剂在无溶剂条件下，收率极高。

  DOI：

  10.1007/bf03246570

文献信息

• Efficient Multi-component Synthesis of Highly Substituted Imidazoles Utilizing P2O5/SiO2 as a Reusable Catalyst
  作者：Hamid Reza Shaterian、Mohammad Ranjbar、Kobra Azizi

  DOI：10.1002/cjoc.201180293

  日期：2011.8

  gel (P2O5/SiO2) has been used as an efficient and reusable catalyst for the one‐pot pseudo four‐component synthesis of 2,4,5‐trisubstituted imidazoles from benzil or benzoin, aldehydes, and ammonium acetate. It was also used for four‐component preparation of 1,2,4,5‐tetrasubstituted imidazoles from benzil or benzoin, aldehydes, primary amine, and ammonium acetate under thermal solvent‐free conditions

  负载在硅胶（P 2 O 5 / SiO 2）上的五氧化二磷已被用作一种高效且可重复使用的催化剂，用于由苯甲腈或安息香，醛，和醋酸铵。它也可在无热溶剂的条件下用于由苄基或安息香，醛，伯胺和乙酸铵四组分制备1,2,4,5-四取代的咪唑。这种新方法的显着特征是高转化率，更清洁的反应，简单的实验和后处理程序，并且催化剂可以轻松地从反应混合物中分离出来并重复使用几次，而不会损失其活性。
• An environmental friendly approach for the synthesis of highly substituted imidazoles using Brønsted acidic ionic liquid, N-methyl-2-pyrrolidonium hydrogen sulfate, as reusable catalyst
  作者：Hamid Reza Shaterian、Mohammad Ranjbar

  DOI：10.1016/j.molliq.2011.02.012

  日期：2011.4

  Brønsted acidic ionic liquid, N-methyl-2-pyrrolidonium hydrogen sulfate, has been used as an efficient and reusable catalyst for the one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles under thermal solvent-free conditions in excellent yields.

  布朗斯台德酸性离子液体N-甲基-2-吡咯烷鎓硫酸氢盐已被用作一种高效且可重复使用的催化剂，用于在以下条件下一锅合成2,4,5-三取代和1,2,4,5-四取代的咪唑无溶剂的热条件，产率高。
• Surface treating composition for copper and copper alloy and utilization thereof
  申请人：SHIKOKU CHEMICALS CORPORATION

  公开号：US10398028B2

  公开（公告）日：2019-08-27

  A surface treating composition for copper or a copper alloy comprising an imidazole compound and means for using the composition in the soldering of electronic parts to printed wiring boards are disclosed.

  本发明公开了一种包含咪唑化合物的铜或铜合金表面处理组合物，以及在将电子零件焊接到印刷线路板时使用该组合物的方法。
• Ytterbium triflate as an efficient catalyst for one-pot synthesis of substituted imidazoles through three-component condensation of benzil, aldehydes and ammonium acetate
  作者：Li-Min Wang、Yong-Hong Wang、He Tian、Yin-Fang Yao、Jue-Hua Shao、Bo Liu

  DOI：10.1016/j.jfluchem.2006.08.005

  日期：2006.12

  Yb(OTf)(3) has been found to be an extremely efficient catalyst for the preparation of imidazoles derivatives via three-component coupling reactions of benzil, aldehydes and ammonium acetate under mild conditions. The process presented here is operationally simple, environmentally benign and has excellent yield. Furthermore, the catalyst can be recovered conveniently and reused for at least three reaction cycles without any loss of activity. (c) 2006 Elsevier B.V. All rights reserved.
• SURFACE TREATING COMPOSITION FOR COPPER AND COPPER ALLOY AND UTILIZATION THEREOF
  申请人：Shikoku Chemicals Corporation

  公开号：EP2714962B1

  公开（公告）日：2015-07-08