[(3aR,6aS)-6-azido-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[2,3-d][1,3]dioxol-5-yl]methanol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(3aR,6aS)-6-azido-5-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[2,3-d][1,3]dioxol-5-yl]methanol
• 化学式: C9H15N3O5
• 分子量: 245.23
• InChiKey: GUPBGRHABGKBNJ-LOJRBXKRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  82.5
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Novel bicyclonucleoside analogues
  申请人：Imanishi Takeshi

  公开号：US20070270370A1

  公开（公告）日：2007-11-22

  Oligonucleotide analogues which have anti-sense or anti-gene activity, as well as in vivo stability, or pharmaceutically acceptable salts thereof. The oligonucleotide analogues have one or more structural units represented by the following formula (1 a ): provided that when the oligonucleotide has two or more structural units of formula (1 a ), each B is the same or different, wherein B represents a purin-9-yl group or a 2-oxo-1,2-dihydropyrimidin-1-yl group.
• US7217805B2
  申请人：——

  公开号：US7217805B2

  公开（公告）日：2007-05-15
• US7994145B2
  申请人：——

  公开号：US7994145B2

  公开（公告）日：2011-08-09