[(2R)-1-[2-[[6-[3-[(2R,4R,5S)-5-[(2S,4R,5R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,4S,5R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropylamino]-6-oxohexanoyl]amino]ethoxy-methylphosphoryl]oxy-3-[(Z)-2-hexyldodec-3-enoyl]oxypropan-2-yl] (Z)-octadec-9-enoate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(2R)-1-[2-[[6-[3-[(2R,4R,5S)-5-[(2S,4R,5R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,4S,5R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropylamino]-6-oxohexanoyl]amino]ethoxy-methylphosphoryl]oxy-3-[(Z)-2-hexyldodec-3-enoyl]oxypropan-2-yl] (Z)-octadec-9-enoate
• 化学式: C₆₉H₁₂₅N₂O₂₅P
• 分子量: 1413.7
• InChiKey: MTRSJIBGEFOWOE-TVGMBWGKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  97
• 可旋转键数：
  58
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  404
• 氢给体数：
  12
• 氢受体数：
  25

文献信息

• CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION
  申请人：Henry Stephen Micheal

  公开号：US20100184723A1

  公开（公告）日：2010-07-22

  The invention relates to selected carbohydrate-lipid constructs and their use as mimics of ligands for receptors expressed by virus. In particular, the invention relates to the use of selected carbohydrate-lipid constructs in methods of inhibiting virus infection and/or promoting clearance of virus from infected subjects. Carbohydrate-lipid constructs selected for use in these methods where the virus is Human Immunodeficiency Virus (HIV) are provided.
• US8211860B2
  申请人：——

  公开号：US8211860B2

  公开（公告）日：2012-07-03