5-Azido-2-methoxy-6-methyloxane-3,4-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-Azido-2-methoxy-6-methyloxane-3,4-diol
• 化学式: C7H13N3O4
• 分子量: 203.2
• InChiKey: PKXUFEYHGZHRPK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  73.3
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Oligosaccharide conjugates and methods of use
  申请人：THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS

  公开号：US10207006B2

  公开（公告）日：2019-02-19

  There is provided a method of detecting in a sample the presence of an anti-M and/or anti-A and/or anti-C/Y antibody, the method comprising contacting the sample with a diagnostic conjugate provided according to the invention, comprising an oligosaccharide which comprises at least two units of 4,6-dideoxy-4-acylamido-α-pyranose and comprising at least one -(1-3)- link between adjacent 4,6-dideoxy-4-acylamido-α-pyranose units, in which the carbon at position 5 in the pyranose is linked to an R group, where R is independently selected from —CH2OH, —H or an alkyl group having at least one C atom, the oligosaccharide being covalently linked to a non-saccharide molecule or to a surface.

  本发明提供了一种检测样品中是否存在抗-M 和/或抗-A 和/或抗-C/Y 抗体的方法，该方法包括将样品与根据本发明提供的诊断共轭物接触，该诊断共轭物由寡糖组成，寡糖包括至少两个 4,6-二脱氧-4-酰氨基-α-吡喃糖单元，相邻的 4、6-二脱氧-4-酰氨基-α-吡喃糖单元之间至少有一个-(1-3)-连接，其中吡喃糖第 5 位的碳与一个 R 基相连，其中 R 独立地选自-CH2OH、-H 或至少有一个 C 原子的烷基，寡糖与非糖分子或表面共价连接。
• OLIGOSACCHARIDE CONJUGATES AND METHODS OF USE
  申请人：The Secretary of State for Environment, Food and Rural Affairs

  公开号：EP2986986B1

  公开（公告）日：2020-07-15