2,2-Dimethyl-4-[(2-methylpropan-2-yl)oxy]hexane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2-Dimethyl-4-[(2-methylpropan-2-yl)oxy]hexane
• 英文别名: 2,2-dimethyl-4-[(2-methylpropan-2-yl)oxy]hexane
• 化学式: C₁₂H₂₆O
• 分子量: 186.33
• InChiKey: IAGBFTKNABVBKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME
  申请人：THE INSTITUTE FOR DRUG DELIVERY

  公开号：US20160297823A1

  公开（公告）日：2016-10-13

  Disclosed are novel substituted amino triazoles of Formula (I), and pharmaceutically acceptable salts thereof. The compounds of Formula (I) are inhibitors of Acidic mammalian chitinase (AMCase) and are useful, in a non-limiting example, for treating asthma. Also provided are pharmaceutical compositions containing at least one compound of the present invention, or a pharmaceutically acceptable salt, hydrate or solvate thereof, and at least one pharmaceutically acceptable carrier, solvent, adjuvant or diluent, and methods of using such compounds and/or compositions to treat asthma and/or to monitor asthma treatment.