isobutyl cyclopropyl ether | 17204-62-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: isobutyl cyclopropyl ether
• 英文别名: Isobutoxy-cyclopropan；2-Methylpropoxycyclopropane
• CAS: 17204-62-5
• 化学式: C₇H₁₄O
• 分子量: 114.188
• InChiKey: HTWMXQNEAPTSAI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  乙烯基异丁醚 生成 isobutyl cyclopropyl ether
  参考文献：
  名称：

  Schlosser,M. et al., Chemische Berichte, 1971, vol. 104, p. 1921 - 1933

  摘要：

  DOI：

文献信息

• The relative reactivity of olefins in cycloaddition with zinc carbenoid
  作者：J. Nishimura、J. Furukawa、N. Kawabata、M. Kitayama

  DOI：10.1016/s0040-4020(01)98044-5

  日期：1971.1

  The relative reactivity of olefins was determined in the homogeneous reaction with zinc carbenoid generated from diethylzinc and CH2I2. The Hammett ϱ-value for substituted styrenes in this reaction was −1·61. The inductive effect was concluded to be the most influential factor which determines the relative reactivity of olefins in the reaction. The mechanism of the reaction is discussed in comparison

  在与由二乙基锌和CH 2 I 2生成的锌类胡萝卜素的均相反应中确定烯烃的相对反应性。该反应中取代苯乙烯的Hammett ϱ值为-1·61。结论是诱导作用是决定反应中烯烃相对反应性的最重要因素。与其他卡宾和类胡萝卜素反应相比，讨论了该反应的机理。
• Synthesis of cyclopropanes by the reaction of olefins with dialkylzinc and methylene iodide
  作者：J. Furukawa、N. Kawabata、J. Nishimura

  DOI：10.1016/0040-4020(68)89007-6

  日期：1968.1

  A novel synthetic route to cyclopropanes by the reaction of olefins with dialkylzinc and methylene iodide is described. The essential feature of the reaction is similar to that of the Simmons-Smith reaction which involves the treatment of olefins with methylene iodide and zinc-copper couple. However, the novel route gives cyclopropanes more easily and is particularly suitable for the conversion of

  描述了一种通过烯烃与二烷基锌和亚甲基碘反应生成环丙烷的新颖合成途径。该反应的基本特征类似于Simmons-Smith反应的特征，该反应包括用亚甲基碘和锌-铜对处理烯烃。但是，该新方法更容易得到环丙烷，并且特别适合于将阳离子聚合性烯烃例如乙烯基醚转化为相应的环丙烷。当使用Simmons-Smith反应时，这类烯烃有时会因聚合反应而产生较低的环丙烷收率。
• Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof
  申请人：The Trustees of the University of Pennsylvania

  公开号：EP2292779A2

  公开（公告）日：2011-03-09

  Sequences of novel adeno-associated virus capsids and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. AAV-mediated delivery of therapeutic and immunogenic genes using the vectors of the invention is also provided.

  本文提供了新型腺相关病毒外壳和载体的序列以及含有这些序列的宿主细胞。还描述了使用这些宿主细胞和载体生产 rAAV 粒子的方法。还提供了使用本发明的载体以 AAV 为媒介传递治疗基因和免疫基因的方法。
• Bridson-Jones et al., Journal of the Chemical Society, 1951, p. 2999,3006
  作者：Bridson-Jones et al.

  DOI：——

  日期：——
• KAWABATA NARIYOSHI; KAMEMURA ICHIRO; NAKA MICHIHARU, J. AMER. CHEM. SOC., 1979, 101, NO 8, 2139-2145
  作者：KAWABATA NARIYOSHI、 KAMEMURA ICHIRO、 NAKA MICHIHARU

  DOI：——

  日期：——