[3-(2-Chlorophenyl)-5-methylisoxazol-4-yl](phenyl)methanone | 666701-83-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [3-(2-Chlorophenyl)-5-methylisoxazol-4-yl](phenyl)methanone
• 英文别名: [3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]-phenylmethanone
• CAS: 666701-83-3
• 化学式: C₁₇H₁₂ClNO₂
• 分子量: 297.7
• InChiKey: VFCULKCUMBHRKF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  43.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• MODULATORS OF SPERM HYPERMOTILITY AND USES THEREOF
  申请人：Chong Jayhong A.

  公开号：US20150335622A1

  公开（公告）日：2015-11-26

  The invention provides novel compositions and compounds that inhibit CatSper channel activity, that preferentially inhibits sperm hyperactivity over sperm motility, or both. The compounds of the invention are useful as contraceptive agents that may be adminstered to males, females, or concurrently to both sexual partners. The invention further provides methods of conducting drug discovery business and of conducting a reproductive medicine business. The invention also provides methods of identifying compounds that modulate sperm hypermotility.
• US8394840B2
  申请人：——

  公开号：US8394840B2

  公开（公告）日：2013-03-12
• US8952041B2
  申请人：——

  公开号：US8952041B2

  公开（公告）日：2015-02-10
• US9732050B2
  申请人：——

  公开号：US9732050B2

  公开（公告）日：2017-08-15