3-(4-Methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl)propan-1-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-(4-Methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl)propan-1-ol
• 英文别名: 3-(4-methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl)propan-1-ol
• 化学式: C₉H₁₆O₄
• 分子量: 188.22
• InChiKey: GDCSDMVNBUPTML-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• MULTI-ARM POLYMERIC ALKANOATE CONJUGATES
  申请人：Nektar Therapeutics

  公开号：US20190029991A1

  公开（公告）日：2019-01-31

  Among other aspects, provided herein are multi-armed polymer conjugates comprising an alkanoate-linker, compositions comprising such conjugates, and related methods of making and administering the same. Methods of treatment employing such conjugates and related uses are also provided. The conjugates are prepared with high drug loading efficiencies.