1-(2-Amino-4-nitrophenyl)ethanone hydrochloride | 1049728-54-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(2-Amino-4-nitrophenyl)ethanone hydrochloride
• 英文别名: 1-(2-amino-4-nitrophenyl)ethanone;hydrochloride
• CAS: 1049728-54-2
• 化学式: C8H9ClN2O3
• 分子量: 216.62
• InChiKey: IYMVSNFKXCSUBE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  88.9
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• NOVEL SUBTITUTED PYRAZOLO[4, 3-E]DIAZEPINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, USE AS MEDICINAL PRODUCTS AND PROCESSES FOR PREPARING THEM
  申请人：WARNER-LAMBERT COMPANY

  公开号：EP1248787A2

  公开（公告）日：2002-10-16
• [EN] NOVEL SUBSTITUTED PYRAZOLO[4,3-e]DIAZEPINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, USE AS MEDICINAL PRODUCTS AND PROCESSES FOR PREPARING THEM<br/>[FR] NOUVELLES PYRAZOLO [4, 3-E]DIAZEPINES, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, UTILISATION COMME PRODUITS MEDICAUX ET PROCEDES DE PREPARATION
  申请人：WARNER LAMBERT CO

  公开号：WO2001049689A2

  公开（公告）日：2001-07-12

  The invention relates to novel substituted pyrazolo[4,3-e]- diazepines of general formula (I), to pharmaceutical compositions containing them, to their use as medicinal products and to processes for preparing them. The compounds are selective PDE4 inhibitors.