(E)-N-[[4-(1,1-difluoroethyl)phenyl]methoxy]-1-[6-(2H-tetrazol-5-ylmethoxy)pyridin-3-yl]ethanimine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-N-[[4-(1,1-difluoroethyl)phenyl]methoxy]-1-[6-(2H-tetrazol-5-ylmethoxy)pyridin-3-yl]ethanimine
• 化学式: C₁₈H₁₈F₂N₆O₂
• 分子量: 388.4
• InChiKey: CDWYDMYCIHRYRY-WYMPLXKRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  98.2
• 氢给体数：
  1
• 氢受体数：
  9

文献信息

• OXIMINO DERIVATIVES FOR THE TREATMENT OF DYSLIPIDEMIA
  申请人：CADILA HEALTHCARE LIMITED

  公开号：US20160083380A1

  公开（公告）日：2016-03-24

  Compounds of the general formula (I), including their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds and the intermediates involved in their preparation.

  通式（I）的化合物，包括其互变异构体、立体异构体、药用盐、含有它们的药物组合物、其制备方法、这些化合物的用途以及其制备过程中涉及的中间体。
• [EN] OXIMINO DERIVATIVES FOR THE TREATMENT OF DYSLIPIDEMIA<br/>[FR] DÉRIVÉS D'OXIMINO POUR LE TRAITEMENT DE LA DYSLIPIDÉMIE
  申请人：CADILA HEALTHCARE LTD

  公开号：WO2015107541A1

  公开（公告）日：2015-07-23

  The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation.