abrusogenin

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: abrusogenin
• 英文别名: GlcA(b1-2)b-Glc；(2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[(2R,3R,4S,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxane-2-carboxylic acid
• 化学式: C₁₂H₂₀O₁₂
• 分子量: 356.284
• InChiKey: BWAUGERKDLCYMO-YMULZJKBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.9
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  207
• 氢给体数：
  8
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  abrusoside D 在 盐酸 作用下， 反应 2.0h， 生成 abrusogenin
  参考文献：
  名称：

  Abrusoside e, a further sweet-tasting cycloartane glycoside from the leaves of Abrus precatorius

  摘要：

  A novel cycloartane glycoside, designated abrusoside E, has been isolated from the leaves of Abrus precatorius. Its structure was determined as 3 beta-O-[beta-D-glucuronopyranosyl-(1 --> 2)-beta-D-glucopyranosyl](20S,22S)-3 beta,22-dihydroxy-9, 19-cyclolanost-24-en-26,29-dioic acid delta-lactone based upon spectroscopic methods carried out on the parent compound and its mono- and dimethyl esters. While abrusoside E was found to be only marginally sweet, the monomethyl ester proved to be more potently sweet-tasting.

  DOI：

  10.1016/0031-9422(95)00792-x