carbamic acid-(1-ethynyl-cyclopentyl ester) | 98593-32-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: carbamic acid-(1-ethynyl-cyclopentyl ester)
• 英文别名: Carbamidsaeure-(1-aethinyl-cyclopentylester)；(1-Ethynylcyclopentyl) carbamate；(1-ethynylcyclopentyl) carbamate
• CAS: 98593-32-9
• 化学式: C₈H₁₁NO₂
• 分子量: 153.181
• InChiKey: VNYIAHZHEIIQCR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  52.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 光气 、 甲苯 作用下， 生成 carbamic acid-(1-ethynyl-cyclopentyl ester)
  参考文献：
  名称：

  Detecting photosynthetic algal pigments in natural populations using a high-spectral-resolution spectroradiometer

  摘要：

  Reflectance data from a high spectral resolution spectroradiometer were obtained onboard a ship in Plymouth coastal waters. These data were analysed to detect algal photosynthetic accessory pigments for comparison with absorption spectra as measured in the laboratory by a spectrophotometer. The overall spectral characteristics of Plymouth waters allowed identification as to population composition, Derivative analysis of the spectra was used to resolve characteristic peaks of specific pigments. It was determined that chlorophyll pigments, a specific carotenoid and sea water absorption bands were detectable in the reflectance data. Absorption bands of photosynthetic and accessory pigments were assessed through chromatographic pigment analysis.

  DOI：

  10.1080/01431160120387

文献信息

• [EN] SUBSTITUTED ALKYNYLENE COMPOUNDS AS ANTICANCER AGENTS<br/>[FR] COMPOSÉS ALCYNYLÈNE SUBSTITUÉS EN TANT QU'AGENTS ANTICANCÉREUX
  申请人：AURIGENE DISCOVERY TECH LTD

  公开号：WO2019142126A1

  公开（公告）日：2019-07-25

  The present invention relates to substituted alkynylene compounds represented by compound of formula (I) pharmaceutically acceptable salts and stereoisomers thereof. The present invention further provides the methods of preparation of compound of formula (I) and therapeutic uses thereof as anti-cancer agents.

  本发明涉及代表为化合物(I)的取代炔基化合物，其药学上可接受的盐和立体异构体。本发明还提供了化合物(I)的制备方法以及作为抗癌药物的治疗用途。
• SUBSTITUTED ALKYNYLENE COMPOUNDS AS ANTICANCER AGENTS
  申请人：Aurigene Discovery Technologies Limited

  公开号：EP3740473A1

  公开（公告）日：2020-11-25
• Substituted Alkynylene Compounds As Anticancer Agents
  申请人：Aurigene Discovery Technologies Limited

  公开号：US20210379055A1

  公开（公告）日：2021-12-09

  The present invention relates to substituted alkynylene compounds represented by the compounds of formula (I), pharmaceutically acceptable salts and stereoisomers thereof. The present invention further provides the therapeutic uses of the compounds of formula (I) as anti-cancer agents.