hydron;[(2S,3S,4R,5S,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methyl sulfate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: hydron;[(2S,3S,4R,5S,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methyl sulfate
• 化学式: C6H12O9S
• 分子量: 260.22
• InChiKey: OKUVUONOJCDUJY-SXUWKVJYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.62
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  165
• 氢给体数：
  5
• 氢受体数：
  9

文献信息

• Compositions and methods for modulating growth of a genetically modified gut bacterial cell
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：US11254918B2

  公开（公告）日：2022-02-22

  Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.

  本发明提供了用于调节存在于人体器官中的转基因细菌细胞的生长、调节转基因细菌细胞在器官（如肠道）中的生长、取代器官中细菌细胞群的至少一部分以及促进转基因细菌细胞在肠道中定植的组合物和方法。此外，还提供了转基因细菌细胞，例如，包括异源碳水化合物利用基因或基因组的细胞，该基因或基因组具有利用稀有碳水化合物作为碳源的能力。
• COMPOSITIONS AND METHODS FOR MODULATING GROWTH OF A GENETICALLY MODIFIED GUT BACTERIAL CELL
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：US20190055529A1

  公开（公告）日：2019-02-21

  Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.
• Compositions and Methods for Modulating Growth of a Genetically Modified Gut Bacterial Cell
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：US20210054356A1

  公开（公告）日：2021-02-25

  Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.