1-(methoxymethoxy)-9,10-diphenylanthracene | 137345-82-5

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 芳基萘木脂素
• 英文名称: 1-(methoxymethoxy)-9,10-diphenylanthracene
• CAS: 137345-82-5
• 化学式: C₂₈H₂₂O₂
• 分子量: 390.481
• InChiKey: NJRXJHYWSIXODW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-羟基蒽醌 在 palladium on activated charcoal 氢气 、 sodium hydride 、 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 生成 1-(methoxymethoxy)-9,10-diphenylanthracene
  参考文献：
  名称：

  Ortho-metallation of anthracene derivative: problem and solution

  摘要：

  Ortho-metallation of anthracene derivative with alkyllithium is hampered by the preferential attack of the anion to the C(9) and/or C(10) positions. Use of n-BuLi-t-BuOK effected a clean and regioselective metallation at C(2) and subsequent reaction with Me3SiCl or Me3SnCl afforded the corresponding arylsilane or arylstannane in high yields.

  DOI：

  10.1016/s0040-4039(00)92164-6

文献信息

• Method for producing biaryl compound
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20030158419A1

  公开（公告）日：2003-08-21

  There is disclosed a method for producing a biaryl compound of formula (I): 1 wherein R 1 is the same or different and independently denotes a substituted or unsubstituted hydrocarbon group or the like, A and B denote an aromatic hydrocarbon ring having from 6 to 14 carbon atoms or the like, k and m independently denote an integer of from 0 to 5, and 1 denotes an integer of 1 or 2, which method is characterized by reacting an aromatic compound of formula (II): 2 wherein R 1 , k and l denote the same as defined above, and X 1 denotes a leaving group, with a Grignard reagent of formula (III): 3 (R 2 ). 9MgX 2 (IIIg) wherein R 2 , B, and m denote the same as defined above and X 2 denotes chlorine or the like, in the presence of a cyclic ether, or an acyclic ether having two or more ether oxygens in the molecule and a nickel catalyst.

  揭示了一种制备式(I)的联苯化合物的方法：其中R1相同或不同且独立地表示取代或未取代的碳氢化合物基团或类似物，A和B表示具有6至14个碳原子或类似物的芳香碳氢环，k和m独立地表示0至5的整数，l表示1或2的整数，该方法的特征在于将式(II)的芳香化合物：其中R1、k和l的定义与上述相同，X1表示离去基团，与式(III)的格氏试剂反应：其中R2、B和m的定义与上述相同，X2表示氯或类似物，在环醚或分子中具有两个或更多个醚氧原子的无环醚和镍催化剂的存在下。
• Method for producing biaryl compounds
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1312605B1

  公开（公告）日：2007-04-25
• US7122711B2
  申请人：——

  公开号：US7122711B2

  公开（公告）日：2006-10-17
• Ortho-metallation of anthracene derivative: problem and solution
  作者：Takashi Matsumoto、Hirotoshi Kakigi、Keisuke Suzuki

  DOI：10.1016/s0040-4039(00)92164-6

  日期：——

  Ortho-metallation of anthracene derivative with alkyllithium is hampered by the preferential attack of the anion to the C(9) and/or C(10) positions. Use of n-BuLi-t-BuOK effected a clean and regioselective metallation at C(2) and subsequent reaction with Me3SiCl or Me3SnCl afforded the corresponding arylsilane or arylstannane in high yields.