(2S)-2-methyl-2-(methylamino)cyclohexan-1-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S)-2-methyl-2-(methylamino)cyclohexan-1-one
• 化学式: C₈H₁₅NO
• 分子量: 141.21
• InChiKey: GACARISANCFUEB-QMMMGPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] ARYLCYCLOHEXYLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC DISORDERS<br/>[FR] DÉRIVÉS ARYLCYCLOHEXYLAMINE ET LEUR UTILISATION DANS LE TRAITEMENT DE TROUBLES PSYCHIATRIQUES
  申请人：GILGAMESH PHARMACEUTICALS INC

  公开号：WO2021134086A1

  公开（公告）日：2021-07-01

  Provided herein are arylcyclohexylamine derivatives and their use in the treatment of psychiatric disorders.

  本文提供了芳基环己胺衍生物及其在治疗精神疾病中的用途。
• Arylcyclohexylamine derivatives and their use in the treatment of psychiatric disorders
  申请人：Gilgamesh Pharmaceuticals, Inc.

  公开号：US11344510B2

  公开（公告）日：2022-05-31

  Provided herein are arylcyclohexylamine derivatives and their use in the treatment of psychiatric disorders.

  本文提供的是芳基环己胺衍生物及其在治疗精神疾病中的用途。
• ARYLCYCLOHEXYLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC DISORDERS
  申请人：Gilgamesh Pharmaceuticals, Inc.

  公开号：US20220409555A1

  公开（公告）日：2022-12-29

  Provided herein are arylcyclohexylanine derivatives and their use in the treatment of psychiatric disorders.
• [EN] METHODS OF TREATING NEUROPSYCHIATRIC DISORDERS<br/>[FR] MÉTHODES DE TRAITEMENT DE TROUBLES NEUROPSYCHIATRIQUES
  申请人：[en]GILGAMESH PHARMACEUTICALS, INC.

  公开号：WO2022261263A1

  公开（公告）日：2022-12-15

  The disclosure provides, in part, a method of treating a neuropsychiatric disorder in a patient in need thereof, comprising administering to the patient an effective amount of an orexin receptor antagonist and further comprising administering to the patient an effective amount of a serotonin 2A receptor agonist or an NMDA receptor antagonist.