3,4-Dimethoxy-2-(methoxymethyl)oxolane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4-Dimethoxy-2-(methoxymethyl)oxolane
• 化学式: C₈H₁₆O₄
• 分子量: 176.21
• InChiKey: PFPWLRZFWHVNMO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• LATANOPROST-CONTAINING AQUEOUS EYE DROPS AND METHOD FOR INHIBITING ADSORPTION OF LATANOPROST TO RESIN
  申请人：Nakajima Tomoko

  公开号：US20120184552A1

  公开（公告）日：2012-07-19

  The invention provides an aqueous eye drop containing latanoprost, a surfactant, and an aliphatic mono- or di-carboxylic acid having a carbon number of 3-10 or a salt thereof. In addition, the invention provides a method of suppressing adsorption of latanoprost to a resin in an aqueous solution, by adding a surfactant and an aliphatic mono- or di-carboxylic acid having a carbon number of 3-10 or a salt thereof.
• HYDROPHILIC MONOLAYER FILMS
  申请人：MITSUI CHEMICALS, INC.

  公开号：US20170044393A1

  公开（公告）日：2017-02-16

  The invention provides monolayer films excellent in hydrophilicity and transparency which include a crosslinked resin having a surface enriched with hydrophilic groups, and materials which exhibit excellent properties such as hydrophilicity, antifogging properties and antifouling properties by virtue of having the above monolayer films. A monolayer film is fabricated which includes a crosslinked resin obtained by polymerizing a composition including a compound (I) having an anionic hydrophilic group and a functional group with a polymerizable carbon-carbon double bond, and a compound (II) having three or more hydroxyl groups and three or more functional groups with a polymerizable carbon-carbon double bond, the monolayer film having a gradient (Sa/Da) of not less than 1.1 wherein Sa is the surface concentration of the anionic hydrophilic groups in the monolayer film, and Da is the deep concentration of the hydrophilic groups at ½ of the thickness of the monolayer film.
• US9976049B2
  申请人：——

  公开号：US9976049B2

  公开（公告）日：2018-05-22
• [EN] LACTATE DEHYDROGENASE A (LDHA) IRNA COMPOSITIONS AND METHODS OF USE THEREOF<br/>[FR] COMPOSITIONS D'ARNI DE LACTATE DÉSHYDROGÉNASE A (LDHA) ET LEURS PROCÉDÉS D'UTILISATION
  申请人：ALNYLAM PHARMACEUTICALS INC

  公开号：WO2019014530A1

  公开（公告）日：2019-01-17

  The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the LDHA gene, as well as methods of inhibiting epression of LDHA, methods of inhibiting LDHA and HAO1, and methods of treating subjects that would benefit from reduction in expression of LDHA, such as subjects having an oxalate pathway-associated disease, disorder, or condition, using such dsRNA compositions.
• [EN] RNA-EDITING OLIGONUCLEOTIDES AND USES THEREOF<br/>[FR] OLIGONUCLÉOTIDES D'ÉDITION D'ARN ET LEURS UTILISATIONS
  申请人：KORRO BIO INC

  公开号：WO2020154342A1

  公开（公告）日：2020-07-30

  The present disclosure features useful compositions and methods to treat disorders for which deamination of an adenosine in an mRNA produces a therapeutic result, e.g., in a subject in need thereof.