tert-butyl N-tert-butoxycarbonyl-N-[(3S,7S,8R,9S)-8-cyclopent-2-en-1-yloxy-7-hydroxy-9-methyl-2-oxo-oxonan-3-yl]carbamate | 1616806-18-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: tert-butyl N-tert-butoxycarbonyl-N-[(3S,7S,8R,9S)-8-cyclopent-2-en-1-yloxy-7-hydroxy-9-methyl-2-oxo-oxonan-3-yl]carbamate
• 英文别名: tert-butyl N-[(3S,7S,8R,9S)-8-cyclopent-2-en-1-yloxy-7-hydroxy-9-methyl-2-oxooxonan-3-yl]-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamate
• CAS: 1616806-18-8
• 化学式: C₂₄H₃₉NO₈
• 分子量: 469.576
• InChiKey: JDNXSEYXSURKFR-VNXZANIESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  33
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  112
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  tert-butyl N-tert-butoxycarbonyl-N-[(3S,7S,8R,9S)-8-cyclopent-2-en-1-yloxy-7-hydroxy-9-methyl-2-oxo-oxonan-3-yl]carbamate 、 甲酸二酯 在 (1E,4E)-1,5-diphenylpenta-1,4-dien-3-one;palladium 、 1,1'-双(二苯基膦)二茂铁 SiO2 、 EtOAc hexanes 作用下， 以 四氢呋喃 为溶剂， 反应 16.0h， 以to yield the title compound as a yellow oil (160 mg, 74%)的产率得到tert-butyl N-[(3S,7S,8S,9S)-7-allyloxy-8-cyclopent-2-en-1-yloxy-9-methyl-2-oxo-oxonan-3-yl]-N-tert-butoxycarbonyl-carbamate
  参考文献：
  名称：

  MACROCYCLIC PICOLINAMIDES AS FUNGICIDES

  摘要：

  本申请涉及公式(I)的大环吡啶酰胺化合物以及这些化合物作为杀真菌剂的用途。

  公开号：

  US20140187588A1

文献信息

• US9681664B2
  申请人：——

  公开号：US9681664B2

  公开（公告）日：2017-06-20
• [EN] MACROCYCLIC PICOLINAMIDES AS FUNGICIDES<br/>[FR] PICOLINAMIDES MACROCYCLIQUES EN TANT QUE FONGICIDES
  申请人：DOW AGROSCIENCES LLC

  公开号：WO2014105817A1

  公开（公告）日：2014-07-03

  The disclosure relates to macrocyclic picolinamides of Formula (I) and to the use of these compounds as fungicides. The present disclosure also includes a fungicidal composition for the control or prevention of fungal attack comprising the macrocyclic picolinamides of Formula (I) and a phytologically acceptable carrier material. A method is also described for the control or prevention of fungal attack on a plant, including the steps of applying a fungicidally effective amount of one or more of the macrocyclic picolinamides of Formula (I) to at least one of the fungus, the plant, an area adjacent to the plant, and the seed adapted to produce the plant.
• MACROCYCLIC PICOLINAMIDES AS FUNGICIDES
  申请人：Dow Agrosciences LLC

  公开号：US20140187588A1

  公开（公告）日：2014-07-03

  The disclosure relates to macrocyclic picolinamides of Formula (I) and to the use of these compounds as fungicides.

  本公开涉及式(I)的宏环吡啶酰胺，以及这些化合物作为杀菌剂的使用。