2-(Hydroxymethyl)-6-(4-methylphenyl)sulfanyloxane-3,4,5-triol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(Hydroxymethyl)-6-(4-methylphenyl)sulfanyloxane-3,4,5-triol
• 化学式: C₁₃H₁₈O₅S
• 分子量: 286.35
• InChiKey: IQCLIQLFPVKINX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  115
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• N-acetylated sialic acids and related sialosides
  申请人：The Regents of the University of California

  公开号：US11161868B2

  公开（公告）日：2021-11-02

  The present invention provides N-acetyl derivatives of sialic acids, including N-acetyl derivatives of Neu5Ac and Neu5Gc. Methods for preparing related precursors and a variety of sialosides are also disclosed.

  本发明提供了硅烷酸的 N-乙酰基衍生物，包括 Neu5Ac 和 Neu5Gc 的 N-乙酰基衍生物。本发明还公开了制备相关前体和各种sialosides的方法。
• CARBOHYDRATE-MODIFIED GLYCOPROTEINS AND USES THEREOF
  申请人：NEWLINK GENETICS CORPORATION

  公开号：US20160022826A1

  公开（公告）日：2016-01-28

  The present invention provides immunogenic compounds which stimulate immune responses in a subject. The present invention provides compositions comprising an isolated glycoprotein antigen covalently bound at pre-existing carbohydrate residues present on the glycoprotein to a carbohydrate epitope. The present invention also provides a method to induce an immune response in a subject comprising administering the compounds of the invention. The present invention further provides methods of making the compounds of the invention and methods of using the compounds of the invention to stimulate immune responses to infectious disease agents and tumors.
• US9879042B2
  申请人：——

  公开号：US9879042B2

  公开（公告）日：2018-01-30