1,1'-[(1-methyl-1,2-ethanediyl)bis(oxy)]bis-octadecane | 35545-51-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,1'-[(1-methyl-1,2-ethanediyl)bis(oxy)]bis-octadecane
• 英文别名: 1-Dioctadecyloxypropan；1,2-bis-octadecyloxy-propane；Octadecane, 1,1'-[(1-methyl-1,2-ethanediyl)bis(oxy)]bis-；1-(2-octadecoxypropoxy)octadecane
• CAS: 35545-51-8
• 化学式: C₃₉H₈₀O₂
• 分子量: 581.063
• InChiKey: AGGAMJXIHRYGDP-UHFFFAOYSA-N

物化性质

• 沸点：
  617.1±28.0 °C(Predicted)
• 密度：
  0.847±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  18
• 重原子数：
  41
• 可旋转键数：
  37
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• LIPID PARTICLE, NUCLEIC ACID TRANSFER CARRIER, COMPOUND FOR MANUFACTURING NUCLEIC ACID TRANSFER CARRIER, METHOD FOR MANUFACTURING LIPID PARTICLE, AND GENE TRANSFER METHOD
  申请人：FUJIFILM Corporation

  公开号：US20150004695A1

  公开（公告）日：2015-01-01

  The present invention provides a lipid particle which has low cytotoxicity, can stably hold a nucleic acid molecule outside a cell (in blood), and can escape from an endosome and rapidly release the nucleic acid in the cytoplasm; a nucleic acid transfer carrier; a compound for manufacturing a nucleic acid transfer carrier; a method for manufacturing a lipid particle; and a gene transfer method. The lipid particle contains, as constituents, a phospholipid having one or more amino groups and one or more nitrogen-containing heterocyclic groups, a neutral lipid not containing a nitrogen-containing heterocyclic group, a sterol, and a nucleic acid.
• US9540638B2
  申请人：——

  公开号：US9540638B2

  公开（公告）日：2017-01-10