2-(furan-2-ylmethylazaniumyl)-4-(4-methylphenyl)-4-oxobutanoate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(furan-2-ylmethylazaniumyl)-4-(4-methylphenyl)-4-oxobutanoate
• 化学式: C16H17NO4
• 分子量: 287.31
• InChiKey: QDMDEGINDJIUNU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  79.5
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Topical Lightening Composition and Uses Thereof
  申请人：Lyga John W.

  公开号：US20120003168A1

  公开（公告）日：2012-01-05

  The disclosure relates to novel topical lightening compositions a skin depigmenting agent and a vehicle. There is provided a topical lightening composition comprising a substituted-4-oxobutanoic acid, ester, or amide tyrosinase inhibitor, and a vehicle. The depigmenting agents of this disclosure can be used as such or as a pharmaceutically acceptable salt including conventional non-toxic salts which include a metal salt or an alkaline earth metal salt, an ammonium salt, or an organic base salt. The depigmenting agents of this disclosure can be incorporated into any cosmetically-, dermatologically-, or cosmeticatically-acceptable vehicle or carrier normally used for topical application. The compositions and methods of the disclosure are effective to lighten skin, hair, lips, and/or nails.
• US8329149B2
  申请人：——

  公开号：US8329149B2

  公开（公告）日：2012-12-11