3-(8'-pentadecenyl)-anisol | 15071-58-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-(8'-pentadecenyl)-anisol
• 英文别名: Benzene, 1-methoxy-3-(8Z)-8-pentadecenyl-；1-methoxy-3-pentadec-8-enylbenzene
• CAS: 15071-58-6
• 化学式: C₂₂H₃₆O
• 分子量: 316.527
• InChiKey: NLGAKMJVJUUZEQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  23
• 可旋转键数：
  14
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3-(8'-pentadecenyl)-anisol 在 potassium permanganate 、 丙酮 作用下， 生成 8-(3-methoxyphenyl)octanoic acid
  参考文献：
  名称：

  The Importance of Social Context in Cross-Cultural Comparisons: First Graders in Colombia and the United States

  摘要：

  The authors explored the cultural constructs of individualism and collectivism by investigating the prosocial behavior of 1st graders (N = 202; 110 girls, 92 boys) in countries typically classified as collectivist (Colombia, South America) and individualist (United States). Contrary to expectations, U.S. children shared more than Colombian children did. However, U.S. children were more likely to take candy from another child without permission (demonstrating individualism). Results indicated that in both countries sharing was greater with friends than with other fellow classmates, and children frequently reported friendship as the reason they shared. Findings support the importance of the social context, such as the relationship between participants, in cross-cultural research and suggest that simple dichotomies of culture often overlook complex associations between culture and behavioral differences.

  DOI：

  10.1080/00221320209598684
• 作为产物：
  描述：

  腰果籽油 、 碘甲烷 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 6.0h， 以55%的产率得到3-(8'-pentadecenyl)-anisol
  参考文献：
  名称：

  [EN] SYNTHETIC METHOD
  [FR] PROCÉDÉ DE SYNTHÈSE

  摘要：

  该发明涉及一种烯烃重排的方法。在该方法中，至少一种单烯烃在存在二烯烃的情况下进行乙烯基解。该发明还涉及使用二烯烃来促进在单烯烃上进行的乙烯基解反应。

  公开号：

  WO2015114323A1

文献信息

• Isomerizing Hydroformylation of Cashew Nut Shell Liquid
  作者：Swechchha Pandey、Dinesh R. Shinde、Samir H. Chikkali

  DOI：10.1002/cctc.201700717

  日期：2017.10.23

  A small library of bisphosphorus ligands was evaluated in the rhodium‐catalyzed isomerizing hydroformylation (I‐HF) of cashew nut shell liquid (CNSL). The rhodium complex of 1,2‐bis((di‐tert‐butylphosphanyl)methyl)benzene (BDTBPMB; L4) outperformed the other bisphosphite and bisphosphine ligands and unveiled a moderate selectivity of 28 % and 50 % in the I‐HF of CNSL monoene and methoxy‐protected monoene

  在腰果壳油（CNSL）的铑催化的异构化加氢甲酰化（I-HF）中评估了一个小的双磷配体库。1,2-双（（二叔丁基膦酰基）甲基）苯的铑配合物（BDTBPMB; L4）优于其他双亚磷酸酯和双膦配体，并且在CNSL的I-HF中具有28％和50％的中等选择性单烯和甲氧基保护的单烯。分离出所得的醛16-（3-甲氧基苯基）十六醛P1'，并完全确定其身份。双膦配体L4在极富挑战性的CNSL腰果酚（S3）和甲氧基保护的CNSL腰果酚可产生74％的线性选择性，但转化率却有所降低。为了证明我们策略的合成实用性，将获得的醛（源自S3）进行氢化，然后以89％的分离产率分离出所得的3-（16-羟基十六烷基）苯酚（P8）。高压NMR研究表明双赤道BDTBPMB-铑络合物的选择性形成，这可能是出色的线性选择性的原因。
• Valorizing Constituents of Cashew Nut Shell Liquid toward the Sustainable Development of New Drugs against Chagas Disease
  作者：Laís Flávia Nunes Lemes、George E. Magoulas、Andressa Souza de Oliveira、Emile Barrias、Luciana de Camargo Nascente、Renato Granado、Sara Teixeira de Macedo Silva、Nikos Assimomytis、Wanderley de Souza、Maria Laura Bolognesi、Luiz Antonio Soares Romeiro、Theodora Calogeropoulou

  DOI：10.1021/acsinfecdis.3c00076

  日期：2023.7.14

  Six new ether phospholipid analogues encompassing constituents from cashew nut shell liquid as the lipid portion were synthesized in an effort to valorize byproducts of the cashew industry toward the generation of potent compounds against Chagas disease. Anacardic acids, cardanols, and cardols were used as the lipid portions and choline as the polar headgroup. The compounds were evaluated for their

  合成了六种新的醚磷脂类似物，其中包含来自腰果壳液的成分作为脂质部分，以努力提高腰果工业副产品的价值，以产生针对恰加斯病的有效化合物。使用漆树酸、腰果酚和腰果酚作为脂质部分，使用胆碱作为极性头基。评估了这些化合物对克氏锥虫不同发育阶段的体外抗寄生虫活性。发现化合物16和17对克氏锥虫上鞭毛体、锥鞭毛体和细胞内无鞭毛体最有效，对后者的选择性指数分别比现有药物苯硝唑高 32 倍和 7 倍。因此，六分之四的类似物可被视为基于廉价农业废料的恰加斯病新疗法可持续开发的热门化合物。
• Compounds and process for preparation of the same from cashew nut shell liquid (CNSL)
  申请人：Council of Scientific & Industrial Research

  公开号：US10683317B2

  公开（公告）日：2020-06-16

  The present invention relates to isomerizing hydroformylation of plant oils to feedstock chemicals and monomers. More particularly, the present invention relates to compound of formula (I) and process for preparation thereof using isomerizing functionalization of cashew nut shell liquid (CNSL).

  本发明涉及将植物油异构化加氢甲酰化为原料化学品和单体。更具体地说，本发明涉及式（I）化合物及其利用腰果壳液（CNSL）的异构化功能化制备工艺。
• On the Olefinic Nature of Anacardic Acid from Indian Cashew Nut Shell Liquid
  作者：V. J. Paul、Lourdu M. Yeddanapalli

  DOI：10.1021/ja01602a057

  日期：1956.11
• NOVEL COMPOUNDS AND PROCESS FOR PREPARATION OF THE SAME FROM CASHEW NUT SHELL LIQUID (CNSL)
  申请人：Council of Scientific & Industrial Research

  公开号：US20190292209A1

  公开（公告）日：2019-09-26

  The present invention relates to isomerizing hydroformylation of plant oils to feedstock chemicals and monomers. More particularly, the present invention relates to compound of formula (I) and process for preparation thereof using isomerizing functionalization of cashew nut shell liquid (CNSL).