D-吡喃葡萄糖 | 39281-67-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: D-吡喃葡萄糖
• 英文名称: (2S,3S,4S,5S,6S)-6-Hydroxymethyl-tetrahydro-pyran-2,3,4,5-tetraol
• 英文别名: beta-L-gulopyranose；(2S,3S,4S,5S,6S)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
• CAS: 39281-67-9
• 化学式: C₆H₁₂O₆
• 分子量: 180.158
• InChiKey: WQZGKKKJIJFFOK-GNFDWLABSA-N

物化性质

• 沸点：
  410.8±45.0 °C(Predicted)
• 密度：
  1.732±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  110
• 氢给体数：
  5
• 氢受体数：
  6

安全信息

• 海关编码：
  2924199090

反应信息

• 作为反应物：
  描述：

  D-吡喃葡萄糖 以96.7的产率得到
  参考文献：
  名称：

  J. Med. Chem. 1993, 36, 181-195

  摘要：

  DOI：

文献信息

• Bicyclo-octane and bicyclo-nonane derivatives, processes for their preparation and their use as herbicides
  申请人：HER MAJESTY THE QUEEN IN RIGHT OF NEW ZEALAND, DEPARTMENT OF SCIENTIFIC AND INDUSTRIAL RESEARCH, CHEMISTRY DIVISON

  公开号：EP0302599A2

  公开（公告）日：1989-02-08

  Bicyclo-octane and bicyclo-nonane derivatives are described having herbicidal and plant growth regulating properties. The derivatives are based on the general formula

  双环辛烷和双环壬烷衍生物具有除草和植物生长调节性能。这些衍生物基于一般公式。
• Diagnosis and treatment of neonatal encephalopathy
  申请人：InfanDx AG

  公开号：US10514383B2

  公开（公告）日：2019-12-24

  Metabolites and signatures (panels) of metabolites are applicable as biomarkers in clinical diagnosis, in particular for neonatal encephalopathy. They are useful tools in differential clinical diagnosis for early detection of brain injury, determination of brain areas affected by the insults and prediction of adverse neurological outcome and may also be applied in diagnosing disease progression and treatment effect. An in vitro method for predicting the likelihood of neonatal encephalopathy of distinct brain areas, identification of affected brain area(s) of neonatal encephalopathy and risk of brain damage and prognosis and neurological outcome due to identification of the type and extent of damage of distinct brain tissues, in particular of hippocampus and/or basal ganglia, is provided.

  代谢物和代谢物特征（组）可作为生物标记物用于临床诊断，尤其是新生儿脑病的诊断。它们是临床鉴别诊断的有用工具，可用于早期发现脑损伤、确定受损伤影响的脑区和预测不良神经系统结果，还可用于诊断疾病进展和治疗效果。本研究提供了一种体外方法，用于预测不同脑区发生新生儿脑病的可能性、确定新生儿脑病的受影响脑区、脑损伤风险以及由于确定不同脑组织（特别是海马和/或基底节）的损伤类型和程度而导致的预后和神经系统结局。
• Method and Use of Metabolites for the Diagnosis and Differentiation of Neonatal Encephalopathy
  申请人：InfanDx AG

  公开号：US20140308687A1

  公开（公告）日：2014-10-16

  Metabolites and signatures (panels) of metabolites are applicable as biomarkers in clinical diagnosis, in particular for neonatal encephalopathy. They are useful tools in differential clinical diagnosis for early detection of brain injury, determination of brain areas affected by the insults and prediction of adverse neurological outcome and may also be applied in diagnosing disease progression and treatment effect. An in vitro method for predicting the likelihood of neonatal encephalopathy of distinct brain areas, identification of affected brain area(s) of neonatal encephalopathy and risk of brain damage and prognosis and neurological outcome due to identification of the type and extent of damage of distinct brain tissues, in particular of hippocampus and/or basal ganglia, is provided.
• METHOD FOR MODIFYING SUBSTRATE SPECIFICITY OF GLUCOSE DEHYDROGENASE AND AGENT FOR MODIFYING SUBSTRATE SPECIFICITY OF GLUCOSE DEHYDROGENASE
  申请人：KIKKOMAN CORPORATION

  公开号：US20220154242A1

  公开（公告）日：2022-05-19

  An object to modify the substrate specificity of glucose dehydrogenase is provided. Also provided are a method of modifying the substrate specificity of glucose dehydrogenase by using a glucose dehydrogenase substrate specificity modifier, the modifier being a glucose analog and a low molecular weight compound, as well as a glucose dehydrogenase substrate specificity modifier.
• US5217537A
  申请人：——

  公开号：US5217537A

  公开（公告）日：1993-06-08