8-oxo-9-decenoic acid | 1326775-61-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: 8-oxo-9-decenoic acid
• 英文别名: 8-Oxo-9-decenoic acid；8-oxodec-9-enoic acid
• CAS: 1326775-61-4
• 化学式: C₁₀H₁₆O₃
• 分子量: 184.235
• InChiKey: LNNPMTHJAYHCMZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  8-oxo-9-decenoic acid 在 cerium(III) chloride heptahydrate 、 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 反应 1.5h， 以92%的产率得到8-hydroxy-9-decenoic acid
  参考文献：
  名称：

  METHOD FOR PRODUCING 18F-LABELED COMPOUND AND HIGH MOLECULAR COMPOUND TO BE USED IN THE METHOD

  摘要：

  本发明的目的在于解决传统的18F-标记化合物生产方法的问题，即液相合成方法中化合物的纯化问题和固相合成方法中由于反应性降低导致产率不足的问题。提供了一种生产18F-标记化合物的方法，包括：使含有待标记前体化合物的残基和分子中的相转移催化剂残基的高分子化合物与18F-反应；并从高分子化合物中去除18F-标记化合物。

  公开号：

  US20120329968A1
• 作为产物：
  描述：

  1,8-辛二醇 在 sodium hypochlorite 、 2,2,6,6-四甲基哌啶氧化物 、 碘苯二乙酸 、 potassium bromide sodium hydride 、 碳酸氢钠 、 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 四氢呋喃 、 1,4-二氧六环 、 二氯甲烷 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 30.08h， 生成 8-oxo-9-decenoic acid
  参考文献：
  名称：

  METHOD FOR PRODUCING 18F-LABELED COMPOUND AND HIGH MOLECULAR COMPOUND TO BE USED IN THE METHOD

  摘要：

  本发明的目的在于解决传统的18F-标记化合物生产方法的问题，即液相合成方法中化合物的纯化问题和固相合成方法中由于反应性降低导致产率不足的问题。提供了一种生产18F-标记化合物的方法，包括：使含有待标记前体化合物的残基和分子中的相转移催化剂残基的高分子化合物与18F-反应；并从高分子化合物中去除18F-标记化合物。

  公开号：

  US20120329968A1

文献信息

• Method for producing 18F-labeled compound and high molecular compound to be used in the method
  申请人：Takahashi Takashi

  公开号：US09073802B2

  公开（公告）日：2015-07-07

  The present invention aims at solving the problems of conventional methods for producing an 18F-labeled compound, that is, the problem of purification of a compound in a liquid phase synthesis method and the problem of an insufficient yield due to the reduction of reactivity in a solid phase synthesis method. There is provided a method for producing an 18F-labeled compound including: allowing a high molecular compound containing a residue of a precursor compound to be labeled and a residue of a phase transfer catalyst in the molecule thereof to react with 18F−; and removing the 18F-labeled compound from the high molecular compound.

  本发明旨在解决传统方法生产18F标记化合物的问题，即液相合成方法中化合物纯化问题和固相合成方法中由于反应性降低而导致收率不足的问题。提供了一种生产18F标记化合物的方法，包括：使含有前体化合物残基和相转移催化剂残基的高分子化合物与18F-反应标记；并从高分子化合物中去除18F标记化合物。
• METHODE FOR PRODUCING F-LABELLED COMPOUND AND HIGH MOLECULAR COMPOUND TO BE USED IN THE METHOD
  申请人：Tokyo Institute of Technology

  公开号：EP2537854A1

  公开（公告）日：2012-12-26

  The present invention aims at solving the problems of conventional methods for producing an 18F-labeled compound, that is, the problem of purification of a compound in a liquid phase synthesis method and the problem of an insufficient yield due to the reduction of reactivity in a solid phase synthesis method. There is provided a method for producing an 18F-labeled compound including: allowing a high molecular compound containing a residue of a precursor compound to be labeled and a residue of a phase transfer catalyst in the molecule thereof to react with 18F-; and removing the 18F-labeled compound from the high molecular compound.

  本发明旨在解决生产 18F 标记化合物的传统方法中存在的问题，即液相合成方法中的化合物纯化问题和固相合成方法中由于反应活性降低导致产率不足的问题。本发明提供了一种生产 18F 标记化合物的方法，包括：让含有待标记前体化合物残留物的高分子化合物及其分子中的相转移催化剂残留物与 18F- 反应；以及从高分子化合物中去除 18F 标记化合物。
• Adhesive
  申请人：JAPAN SCIENCE AND TECHNOLOGY AGENCY

  公开号：US10011671B2

  公开（公告）日：2018-07-03

  The object of the present invention is to provide a novel adhesive. The characteristics of the present invention is an adhesive comprising an organic polymer having a main chain formed by a water-soluble polymer unit, and a hydrophilic organic group and a self-assembling group bonded to the water-soluble polymer unit; and a curing agent.

  本发明的目的是提供一种新型粘合剂。本发明的特征是一种粘合剂，包括一种有机聚合物，其主链由一个水溶性聚合物单元、一个亲水性有机基团和一个与水溶性聚合物单元键合的自组装基团构成；以及一种固化剂。
• ADHESIVE
  申请人：JAPAN SCIENCE AND TECHNOLOGY AGENCY

  公开号：US20160200952A1

  公开（公告）日：2016-07-14

  The object of the present invention is to provide a novel adhesive. The characteristics of the present invention is an adhesive comprising an organic polymer having a main chain formed by a water-soluble polymer unit, and a hydrophilic organic group and a self-assembling group bonded lo the water-soluble polymer unit; and a curing agent.
• FUNCTIONAL POLYMER MEMBRANE, STACK OR DEVICE PROVIDED WITH FUNCTIONAL POLYMER MEMBRANE, AND METHOD OF PRODUCING FUNCTIONAL POLYMER MEMBRANE
  申请人：FUJIFILM Corporation

  公开号：US20170152362A1

  公开（公告）日：2017-06-01

  Provided is a functional polymer membrane including a porous support; and a resin layer and an auxiliary layer which are supported by the porous support, in which both of the resin layer and the auxiliary layer contain an ion exchange polymer having one of an anion exchange group and a cation exchange group, a charge of the ion exchange group of the ion exchange polymer included in the resin layer is opposite to a charge of the ion exchange group of the ion exchange polymer included in the auxiliary layer, and both of the ion exchange polymers respectively included in the resin layer and the auxiliary layer are polymers having a unit obtained from an acryloyl group which may have an alkyl group at the α-position; a stack or a device provided with a functional polymer membrane; and a method of producing, a functional polymer membrane.