(-)-(4,6-O-Benzylidene)phenyl-beta-D-glucopyranoside

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (-)-(4,6-O-Benzylidene)phenyl-beta-D-glucopyranoside
• 英文别名: 6-phenoxy-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-7,8-diol
• 化学式: C₁₉H₂₀O₆
• 分子量: 344.4
• InChiKey: VEVONSHXUHYXKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  77.4
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Method of Producing Macrocyclic Ketone, and Intermediate Thereof
  申请人：Matsuda Hiroyuki

  公开号：US20070287870A1

  公开（公告）日：2007-12-13

  A process for producing muscone by methyl addition to the 1,4-conjugation of 2-cyclopentadecenone. By the process, muscone is produced in high yield not under reaction condition including an extremely low temperature and a low concentration but under practical condition. The process comprises subjecting 2-cyclopentadecenone to a 1,4-conjugation addition reaction with an organometallic methylation reagent in the presence of a copper or nickel catalyst and an enol anion scavenger to obtain a 3-methyl-1-cyclopentadecene derivative represented by General Formula (II) and then solvolyzing the enol moiety of the 3-methyl-1-cyclopentadecene derivative to obtain muscone.

  通过对2-环戊十五烯酮的1,4-共轭加成进行甲基化反应制备肉麝香的方法。该过程在实用条件下而非包括极低温度和低浓度的反应条件下高产肉麝香。该过程包括将2-环戊十五烯酮与有机金属甲基试剂在铜或镍催化剂和烯醇阴离子清除剂的存在下进行1,4-共轭加成反应，以获得由通式（II）表示的3-甲基-1-环戊十五烯衍生物，然后溶解3-甲基-1-环戊十五烯衍生物的烯醇基团以获得肉麝香。
• PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED COMPOUNDS
  申请人：MINNAARD Adriaan Jacobus

  公开号：US20080275274A1

  公开（公告）日：2008-11-06

  Process for the preparation of enantiomerically enriched compounds of formula Ar—C(R 1 )—C(R 2 )-Z wherein Ar represents an optionally substituted (hetero)aryl group R 1 and R 2 , each independently, represent H, an alkyl, (hetero)aryl, dialkylamino, amido, thioether, alkoxy or aryloxy group with the proviso that not both R 1 and R 2 represent H, or R 1 and R 2 form together with the C-atoms to which they are bound a (hetero)alkyl or (hetero)alkenyl ring and Z represents an electron withdrawing group, in which process a boronic acid derivate of formula Ar—B(OR 3 )OR 4 or its anhydride, wherein R 3 and R 4 , each independently, represent H or an alkyl group, is reacted with an olefinic unsaturated compound of formula R 2 —C═C—(R 1 )Z in the presence of a transition metal catalyst comprising a transition metal chosen from Cu and group VIII and an enantiomerically enriched ligand L, having formula (I) where C n together with the two O-atoms and the P-atom forms a substituted or nonsubstituted ring with 2-6 C-atoms, R 5 and R 6 each independently represent H, an optionally substituted alkyl, aryl, alkaryl, or aralkyl group, or the group of formula (II) wherein C n 1 may have the same meanings as given for C n and B represents a bridging group, or R 5 and R 6 may form a heterocyclic ring together with the N-atom to which they are bound.
• US7479574B2
  申请人：——

  公开号：US7479574B2

  公开（公告）日：2009-01-20
• US7732365B2
  申请人：——

  公开号：US7732365B2

  公开（公告）日：2010-06-08