Hydrazinoadenosine impurity 2

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷
• 英文名称: Hydrazinoadenosine impurity 2
• 英文别名: 2-(6-amino-2-hydrazinylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• 化学式: C₁₀H₁₅N₇O₄
• 分子量: 297.27
• InChiKey: BAYFDGKAUSOEIS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.5
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  178
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• 2-BENZYLIDENE HYDRAZINOADENOSINE COMPOUNDS HAVING A2A ADENOSINE RECEPTOR AGONISTIC ACTIVITY
  申请人：ACADEMY OF MILITARY MEDICAL SCIENCES

  公开号：US20220378816A1

  公开（公告）日：2022-12-01

  2-Benzylidene hydrazinoadenosine compounds having A 2A adenosine receptor agonistic activity, represented by a general Formula (I) and pharmaceutical compositions containing the same. The compounds and compositions can act as A 2A adenosine receptor agonist to serve as medicaments.