5,7-Dodecanedione | 16387-74-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5,7-Dodecanedione
• 英文别名: dodecane-5,7-dione
• CAS: 16387-74-9
• 化学式: C₁₂H₂₂O₂
• 分子量: 198.305
• InChiKey: PYAINELFQCMEIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5,7-Dodecanedione 在 beta-diketone hydrolase 水 作用下， 反应 15.0h， 生成 2-己酮 、 正戊酸
  参考文献：
  名称：

  Sakai, Kiyofumi; Hamada, Nobutake; Watanabe, Yasuto, Agricultural and Biological Chemistry, 1986, vol. 50, # 4, p. 989 - 996

  摘要：

  DOI：
• 作为产物：
  描述：

  5,7-十二烷二炔 在 甲酸 作用下， 反应 40.0h， 以47%的产率得到5,7-Dodecanedione
  参考文献：
  名称：

  Hydration of alkynes in anhydrous medium with formic acid as water donor

  摘要：

  Formic acid has been found to hydrate alkynes in the absence of water to give oxo products and carbon monoxide. The scope of the reaction of alkynes and formic acid has been delineated. Hydrocarbon alkynes were found to be reactive in the absence of catalyst. Functionalized alkynes, in particular oxygenated alkynes, are inert toward formic acid but can be activated catalytically with Ru3(CO)12. Consequently, all the tested types of alkynes were found to give oxo products and CO with formic acid. The mechanism of the reaction was examined. With some alkynes, the primary oxo products underwent secondary reactions that gave rise to unexpected products.

  DOI：

  10.1021/jo00078a023

文献信息

• [EN] COMPOUNDS<br/>[FR] COMPOSÉS
  申请人：TESARO INC

  公开号：WO2018136887A1

  公开（公告）日：2018-07-26

  Compounds of formula (IA) and formula (IB), which are useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase, are provided. Also provided are pharmaceutical compositions, kits comprising said compounds, and methods and uses pertaining to said compounds.

  提供了式(IA)和式(IB)的化合物，这些化合物作为吲哚胺2,3-双加氧酶和/或色氨酸双加氧酶的抑制剂具有用途。还提供了包含这些化合物的药物组合物、套件以及与这些化合物相关的方法和用途。
• POLYMERIC COMPOUND CONTAINING REPEATING UNIT HAVING 2-OXATRICYCLO[4.2.1.04,8]NONAN-3-ONE RING, AND PHOTORESIST RESIN COMPOSITION
  申请人：DAICEL CHEMICAL INDUSTRIES, LTD.

  公开号：EP1681307A1

  公开（公告）日：2006-07-19

  A polymeric compound of the invention includes at least one monomer unit represented by the following formula (I); wherein Ra is a hydrogen atom, a halogen atom, an alkyl group of 1 to 6 carbon atoms or an haloalkyl group of 1 to 6 carbon atoms; each of R1 and R2 is identical to or different from a hydrogen atom or a hydrocarbon group, provided that at least one of R1 and R2 is a hydrocarbon group; R1 and R2 may be bonded together to form a ring with an adjacent carbon atom; and each of R3, R4, R5, R6, R7, R8 and R9 is identical to or different from a hydrogen atom or a hydrocarbon group. This polymeric compound has not only high substrate adhesion and high etching resistance but also high solubility for a resist solvent.

  本发明的聚合化合物包括至少一个由下式 (I) 表示的单体单元； 其中，Ra 是氢原子、卤素原子、1 至 6 个碳原子的烷基或 1 至 6 个碳原子的卤代烷基；R1 和 R2 中的每一个与氢原子或烃基相同或不同，条件是 R1 和 R2 中至少有一个是烃基；R1 和 R2 可键合在一起，与相邻的碳原子形成一个环；R3、R4、R5、R6、R7、R8 和 R9 中的每一个与氢原子或烃基相同或不同。这种聚合化合物不仅具有高基底附着力和高抗蚀刻性，而且对抗蚀剂溶剂具有高溶解性。
• METHOD FOR REMOVING FLUORINE-CONTAINING COMPOUND FROM WASTE WATER
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：EP3862324A1

  公开（公告）日：2021-08-11

  Provided is a method for removing a fluorine-containing compound from discharge water including bringing discharge water containing two or more fluorine-containing compounds represented by the following general formula (1) or (2) into contact with an adsorbent to allow the adsorbent to adsorb the two or more fluorine-containing compounds:         General Formula (1):     (H-(CF2)m-COO)pM1 wherein m is 3 to 19, M1 is H, a metal atom, NRb4, where Rb is the same or different and is H or an organic group having 1 to 10 carbon atoms, imidazolium optionally having a substituent, pyridinium optionally having a substituent, or phosphonium optionally having a substituent; and p is 1 or 2,         General Formula (2) :     (H-(CF2)n-SO3)qM2 wherein n is 4 to 20; M2 is H, a metal atom, NRb4, where Rb is the same as above, imidazolium optionally having a substituent, pyridinium optionally having a substituent, or phosphonium optionally having a substituent; and q is 1 or 2.

  本发明提供了一种从排放水中去除含氟化合物的方法，包括将含有两种或两种以上由以下通式（1）或（2）表示的含氟化合物的排放水与吸附剂接触，使吸附剂吸附两种或两种以上含氟化合物： 通式 (1)：(H-(CF2)m-COO)pM1 其中 m 为 3 至 19，M1 为 H、金属原子、NRb4（其中 Rb 相同或不同，且为 H 或具有 1 至 10 个碳原子的有机基团）、可选具有取代基的咪唑鎓、可选具有取代基的吡啶鎓或可选具有取代基的膦；p 为 1 或 2、 通式(2)：(H-(CF2)n-SO3)qM2 其中 n 为 4 至 20；M2 为 H、金属原子、NRb4（其中 Rb 与上述相同）、任选具有取代基的咪唑鎓、任选具有取代基的吡啶鎓或任选具有取代基的膦；以及 q 为 1 或 2。
• POLYTETRAFLUOROETHYLENE PRODUCTION METHOD
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：EP3862368A1

  公开（公告）日：2021-08-11

  Provided is a method for producing polytetrafluoroethylene comprising polymerizing tetrafluoroethylene in an aqueous medium in the presence of a nucleating agent and a hydrocarbon anionic surfactant to obtain polytetrafluoroethylene, wherein a total amount of the nucleating agent and the hydrocarbon anionic surfactant at the initiation of polymerization is more than 50 ppm based on the aqueous medium.

  本发明提供了一种生产聚四氟乙烯的方法，该方法包括在成核剂和烃阴离子表面活性剂存在下，在水介质中聚合四氟乙烯，以获得聚四氟乙烯，其中在聚合开始时，成核剂和烃阴离子表面活性剂的总量以水介质为基准超过 50 ppm。
• COMPOSITION, STRETCHED BODY AND METHOD OF MANUFACTURING THEREOF
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：EP3922435A1

  公开（公告）日：2021-12-15

  A composition having a breaking strength of 10.0 N or more, containing a polytetrafluoroethylene, and substantially free from a compound represented by the following general formula (3):         General Formula (3):     (H-(CF2)8-SO3)qM2 wherein M2 is H, a metal atom, NR54, where each R5 may be the same or different and is H or an organic group having 1 to 10 carbon atoms, imidazolium optionally having a substituent, pyridinium optionally having a substituent, or phosphonium optionally having a substituent; and q is 1 or 2.

  一种断裂强度为 10.0 N 或以上的组合物，含有聚四氟乙烯，且基本上不含下式 (3) 所代表的化合物： 通式 (3)：(H-(CF2)8-SO3)qM2 其中 M2 是 H、金属原子、NR54，其中每个 R5 可以相同或不同，并且是 H 或具有 1 至 10 个碳原子的有机基团、任选具有取代基的咪唑鎓、任选具有取代基的吡啶鎓或任选具有取代基的鏻；以及 q 是 1 或 2。