5-Bromo-2-(4-fluorophenoxy)pyrimidine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-Bromo-2-(4-fluorophenoxy)pyrimidine
• 化学式: C₁₀H₆BrFN₂O
• 分子量: 269.073
• InChiKey: YNUWXJLUUQKHAJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  35
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY
  申请人：OTSUKA PHARMACEUTICAL CO., LTD.

  公开号：US20210403456A1

  公开（公告）日：2021-12-30

  The present invention provides a novel heterocyclic compound represented by Formula [I] and a salt thereof: wherein the symbols are as defined in the specification, which is useful for treating, preventing and/or diagnosing seizure and the like in disease involving epileptic seizure or convulsive seizure (including multiple drug resistant seizure, refractory seizure, acute symptomatic seizure, febrile seizure and status epilepticus), as well as a medical use therefor.