3,3',4-trimethoxybiphenyl | 58005-57-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,3',4-trimethoxybiphenyl
• 英文别名: 3,4,3'-Trimethoxybiphenyl；3,3a(2),4-Trimethoxy-1,1a(2)-biphenyl；1,2-dimethoxy-4-(3-methoxyphenyl)benzene
• CAS: 58005-57-5
• 化学式: C₁₅H₁₆O₃
• 分子量: 244.29
• InChiKey: UOKGWVUFZSKNAM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3,3',4-trimethoxybiphenyl 在 tert-butylammonium hexafluorophosphate(V) 作用下， 以23%的产率得到
  参考文献：
  名称：

  氧化条件下多环芳烃异构化和重排的研究–阳极与试剂介导的反应

  摘要：

  活性钼阳极上的有机电转化可形成熔融的芳烃。在阳极条件下实现了高化学选择性，并且通过与MoCl 5介导的反应结果进行比较，观察到了试剂诱导的选择性。多环芳烃如菲，苯并菲，菊酯或螺旋烯的收率高达87％，是有选择地获得的，在某些情况下，异常的重排对于产物的形成至关重要。

  DOI：

  10.1016/j.electacta.2019.02.041
• 作为产物：
  描述：

  间溴苯甲醚 、 3,4-二甲氧基苯硼酸 在 bis(1,1'-ethylene-3,3'-divinylimidazole-2,2'-diylidene)nickel(II) dibromide dihydrate 、 potassium carbonate 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 8.0h， 以99%的产率得到3,3',4-trimethoxybiphenyl
  参考文献：
  名称：

  Highly active homoleptic nickel(II) bis-N-heterocyclic carbene catalyst for Suzuki–Miyaura and Heck cross-coupling reactions

  摘要：

  New homoleptic nickel(II) biscarbene complex was synthesized and structurally characterized. The complex depicted the excellent catalytic activities with only 3 mol% catalyst loading along with wide substrate scope for the Suzuki-Miyaura cross-coupling reactions (twenty six examples) and Heck coupling reactions (eighteen examples). (C) 2018 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2018.10.028

文献信息

• Application of the ‘resin-capture–release’ methodology to macrocyclisation via intramolecular Suzuki–Miyaura coupling
  作者：Virginie Lobrégat、Gilles Alcaraz、Hugues Bienaymé、Michel Vaultier

  DOI：10.1039/b101156l

  日期：——

  Aryl boronic acids can be trapped by an ammonium hydroxide-form Dowex® Ion Exchangers resin (D-OH−) leading to polymer-ionically bound borates and cyclized, when properly designed, into macroheterocycles under Suzuki–Miyaura coupling conditions.

  芳基硼酸可以通过氨水基的Dowex®离子交换树脂（D-OH⁻）被捕获，导致聚合与离子结合的硼酸盐，并在适当设计下，在铃木－宫浦耦合条件下环化成宏观杂环结构。
• SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES
  申请人：University of Utah Research Foundation

  公开号：US20200354356A1

  公开（公告）日：2020-11-12

  Methods of detecting a non-explosive analyte can include exposing a sensor compound to a non-explosive analyte and displaying a change in the sensor compound upon exposure of the sensor compound to the non-explosive analyte. A variety of sensor compounds for detecting a target analyte, including both explosive and non-explosive analytes, is also described. Sensor devices for detecting a target analyte can include a substrate and a sensor compound positioned on the substrate in a plurality of detection zones.
• Highly active homoleptic nickel(II) bis-N-heterocyclic carbene catalyst for Suzuki–Miyaura and Heck cross-coupling reactions
  作者：Muthukumaran Nirmala、Sathyanarayana Arruri、Moulali Vaddamanu、Ramesh Karupnaswamy、Maruthupandi Mannarsamy、Mannem Adinarayana、Prabusankar Ganesan

  DOI：10.1016/j.poly.2018.10.028

  日期：2019.1

  New homoleptic nickel(II) biscarbene complex was synthesized and structurally characterized. The complex depicted the excellent catalytic activities with only 3 mol% catalyst loading along with wide substrate scope for the Suzuki-Miyaura cross-coupling reactions (twenty six examples) and Heck coupling reactions (eighteen examples). (C) 2018 Elsevier Ltd. All rights reserved.
• Investigations on isomerization and rearrangement of polycyclic arenes under oxidative conditions – Anodic versus reagent-mediated reactions
  作者：Sebastian B. Beil、Peter Franzmann、Timo Müller、Maximilian M. Hielscher、Tobias Prenzel、Dennis Pollok、Nicole Beiser、Dieter Schollmeyer、Siegfried R. Waldvogel

  DOI：10.1016/j.electacta.2019.02.041

  日期：2019.4

  formation of fused arenes. High chemoselectivity was achieved under anodic conditions, and a reagent-induced selectivity was observed by comparison with results of MoCl5-mediated reactions. Polycyclic arenes like phenanthrenes, triphenylenes, chrysenes, or helicenes were selectively obtained in yields up to 87% and in some cases unusual rearrangements were crucial for the product formation.

  活性钼阳极上的有机电转化可形成熔融的芳烃。在阳极条件下实现了高化学选择性，并且通过与MoCl 5介导的反应结果进行比较，观察到了试剂诱导的选择性。多环芳烃如菲，苯并菲，菊酯或螺旋烯的收率高达87％，是有选择地获得的，在某些情况下，异常的重排对于产物的形成至关重要。