N,N'-1,4-亚苯基二甘氨酸 | 10097-07-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N,N'-1,4-亚苯基二甘氨酸
• 英文名称: N,N'-1,4-phenylenediglycine
• 英文别名: N,N'-Bis-carboxymethyl-p-phenylendiamin；N,N'-(1,4-phenylene)bis(glycine)；N,N'-p-phenylene-bis-glycine；N,N'-p-Phenylen-bis-glycin；D-p-carboxymethylaminophenylglycine；p-Phenylendiglycin；N,N'-1,4-Phenylenedi-glycine；2-[4-(carboxymethylamino)anilino]acetic acid
• CAS: 10097-07-1
• 化学式: C₁₀H₁₂N₂O₄
• 分子量: 224.216
• InChiKey: AEMHLEHHONVKCQ-UHFFFAOYSA-N

物化性质

• 沸点：
  587.1±45.0 °C(Predicted)
• 密度：
  1.488±0.06 g/cm3(Predicted)
• 溶解度：
  溶于二甲基亚砜

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  98.7
• 氢给体数：
  4
• 氢受体数：
  6

安全信息

• 海关编码：
  2922499990

反应信息

• 作为反应物：
  描述：

  N,N'-1,4-亚苯基二甘氨酸 在 溶剂黄146 、 sodium nitrite 作用下， 以 水 为溶剂， 以77%的产率得到N,N’-dinitroso-p-phenylenediamine-N,N’-diacetic acid
  参考文献：
  名称：

  通过 Sydnone-炔烃环加成的全芳香高性能热固性塑料

  摘要：

  我们开发了一种高效的合成平台，用于制备基于双官能 sydnone 与三官能炔烃的 1,3-偶极环加成反应的新型高性能热固性塑料。这些可加工材料具有出色的热稳定性，520 °C 下的 Td5% 和 225 °C 下每天的重量损失 <0.1%（均在空气中）。这种性能的关键是起始官能团的稳定性，它允许通过简单的热活化进行反应性 B 阶跃，以提供完全芳香族和高度交联的基于聚吡唑的热固性材料。

  DOI：

  10.1021/jacs.6b03381
• 作为产物：
  描述：

  N,N'-二乙酰-1,4-苯二胺 在 硫酸 、 sodium hydride 作用下， 生成 N,N'-1,4-亚苯基二甘氨酸
  参考文献：
  名称：

  High-Performance Caged Nitric Oxide:  A New Molecular Design, Synthesis, and Photochemical Reaction

  摘要：

  DOI：

  10.1021/ja962839d

文献信息

• [EN] NOVEL COMPOSITIONS FOR LABELING BIOMOLECULES AND METHODS USING SAME<br/>[FR] NOUVELLES COMPOSITIONS DE MARQUAGE DE BIOMOLÉCULES ET PROCÉDÉS LES UTILISANT
  申请人：UNIV CALIFORNIA

  公开号：WO2017196544A1

  公开（公告）日：2017-11-16

  The present invention includes novel compounds useful for labeling biomolecules. The present invention further includes a novel method of labeling a biomolecule using a compound of the invention. The present invention further includes a novel method of imaging a biomolecule using a compound of the invention.

  本发明包括用于标记生物分子的新化合物。本发明还包括使用该发明的化合物标记生物分子的新方法。本发明还包括使用该发明的化合物成像生物分子的新方法。
• DE145062
  申请人：——

  公开号：——

  公开（公告）日：——
• Fulleropyrrolidine End-Capped Molecular Wires for Molecular Electronics—Synthesis, Spectroscopic, Electrochemical, and Theoretical Characterization
  作者：Jakob Kryger Sørensen、Jeppe Fock、Anders Holmen Pedersen、Asger B. Petersen、Karsten Jennum、Klaus Bechgaard、Kristine Kilså、Victor Geskin、Jérôme Cornil、Thomas Bjørnholm、Mogens Brøndsted Nielsen

  DOI：10.1021/jo102066x

  日期：2011.1.7

  In continuation of previous studies showing promising metal molecule contact properties a variety of C-60 end-capped "molecular wires" for molecular electronics were prepared by variants of the Prato 1,3-dipolar cycloaddition reaction. Either benzene or fluorene was chosen as the central wire, and synthetic protocols for derivatives terminated with one or two fullero[c]pyrrolidine "electrode anchoring" groups were developed. An aryl-substituted aziridine could in some cases be employed directly as the azomethine ylide precursor for the Prato reaction without the need of having an electron-withdrawing ester group present. The effect of extending the pi-system of the central wire from 1,4-phenylenediamine to 2,7-fluorenediamine was investigated by absorption, fluorescence, and electrochemical methods. The central wire and the Co-60 end-groups were found not to electronically communicate in the ground state. However, the fluorescence of C60 was quenched by charge transfer from the wire to C-60. Quantum chemical calculations predict and explain the collapse of coherent electronic transmission through one of the fulleropyrrolidine-terminated molecular wires.
• Fullerene-Based Anchoring Groups for Molecular Electronics
  作者：Christian A. Martin、Dapeng Ding、Jakob Kryger Sørensen、Thomas Bjørnholm、Jan M. van Ruitenbeek、Herre S. J. van der Zant

  DOI：10.1021/ja804699a

  日期：2008.10.8

  We present results on a new fullerne-based anchoring group for molecular electronics. Using lithographic mechanically controllable break junctions in vaccum we have determined the conductance and stability of single-molecule junctions of 1,4-bis(fullero[c]pyrrolidin-1-yl)benzene. The compound can be self-assembled from solution and has a low-bias conductance of 3 x 10(-4) G(0). Compared to 1,4-benzenedithiol the fullerene-anchored molecule exhibits a considerably lower conductance spread. In addition, the signature of the new compound in histograms is more significant than that of 1,4-benzenediamine, probably owing to a more stable adsorption motif. Statistical analyses of the breaking of the junctions confirm the stability of the fullerene-gold bond.
• Zimmermann; Knyrim, Chemische Berichte, 1883, vol. 16, p. 515
  作者：Zimmermann、Knyrim

  DOI：——

  日期：——