4-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
• 英文别名: 4-(4-chlorophenyl)-3-methyl-1H-1,2,4-triazole-5-thione
• 化学式: C₉H₈ClN₃S
• mdl: MFCD04057385
• 分子量: 225.702
• InChiKey: OWLOUYHMVYBXQJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.111
• 拓扑面积：
  59.7
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-acetyl-4-(4-chlorophenyl)thiosemicarbazide 在 sodium hydroxide 作用下， 以76%的产率得到4-(4-chlorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
  参考文献：
  名称：

  氨基硫脲和 S-三唑衍生物的抗菌和理化特性

  摘要：

  图形摘要摘要已合成了两个系列氨基硫脲衍生物和三个系列的s-三唑衍生物。测试了所有这些化合物对革兰氏阳性和革兰氏阴性细菌菌株的体外抗菌活性。在测试的氨基硫脲衍生物中，检测到两种具有 3-/4-甲苯基取代（1 l，1 m）的 1-甲酰氨基硫脲的最佳生物活性（MIC 范围在 31.25 和 250 μg/mL 之间）。所有测试的 s-三唑衍生物的抗菌活性都低于它们的无环前体。

  DOI：

  10.1080/10426507.2014.902831

文献信息

• Lin, Yang-i; Petty, S. R.; Lowell, F. M., Journal of Heterocyclic Chemistry, 1980, vol. 17, p. 1077 - 1080
  作者：Lin, Yang-i、Petty, S. R.、Lowell, F. M.、Perkinson, N. A.、Lang, S. A.

  DOI：——

  日期：——
• Novel compound, polymerizable composition, color filter and production method thereof, solid-state imaging device, and planographic printing plate precursor
  申请人：FUJIFILM Corporation

  公开号：EP2141206B1

  公开（公告）日：2014-12-03
• LIN Y.; PETTY S. R.; LOVELL F. M.; PERKINSON N. A.; LANG S. A., J. HETEROCYCL. CHEM., 1980, 17, NO 5, 1077-1080
  作者：LIN Y.、 PETTY S. R.、 LOVELL F. M.、 PERKINSON N. A.、 LANG S. A.

  DOI：——

  日期：——
• Photosensitive Compositions, Curable Compositions, Novel Compounds, Photopolymerizable Compositions, Color Filters, and Planographic Printing Plate Precursors
  申请人：Tsuchimura Tomotaka

  公开号：US20090023085A1

  公开（公告）日：2009-01-22

  A photosensitive composition includes a compound represented by Formula (I) and a curable composition contains the compound of Formula (I) and a polymerizable compound. A compound is represented by a Formula (1) and a photocurable composition contains the compound of Formula (1) and a polymerizable compound. In Formula (I), R, R 1 and R 2 each independently represent a hydrogen atom or a monovalent substituent. In Formula (1), R and B each independently represent a monovalent substituent, A represents a divalent organic group, and Ar represents an aryl group.
• NOVEL COMPOUND, POLYMERIZABLE COMPOSITION, COLOR FILTER, AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, AND PLANOGRAPHIC PRINTING PLATE PRECURSOR
  申请人：Makino Masaomi

  公开号：US20110267714A1

  公开（公告）日：2011-11-03

  Provided is a photopolymerizable composition that is highly sensitive to light having wavelengths of 365 nm and 405 nm, and is capable of forming a curable film that can suppress deterioration in physical properties of the film due to heat-aging. The photopolymerizable composition include: (A) an oxime polymerization initiator which includes a condensed ring formed by containing two or more rings selected from an aromatic ring and a heterocyclic ring, and a cyclic structure which is connected to the condensed ring, the cyclic structure containing a carbonyl group and having an oxime group directly connected to the carbonyl group; and (B) a polymerizable compound.