2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis[bis(2,4,6-trimethylphenyl)phosphino]butane | 1024202-75-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis[bis(2,4,6-trimethylphenyl)phosphino]butane
• 英文别名: [5-[Bis(2,4,6-trimethylphenyl)phosphanylmethyl]-2,2-dimethyl-1,3-dioxolan-4-yl]methyl-bis(2,4,6-trimethylphenyl)phosphane
• CAS: 1024202-75-2
• 化学式: C₄₃H₅₆O₂P₂
• 分子量: 666.864
• InChiKey: ZYTDIYOGIBUDHO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.6
• 重原子数：
  47
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] HYDROFORMYLATION PROCESS<br/>[FR] PROCÉDÉ D'HYDROFORMYLATION
  申请人：LYONDELL CHEMICAL TECH LP

  公开号：WO2010132087A1

  公开（公告）日：2010-11-18

  A process for the production of 4-hydroxybutyraldehyde is described. The process comprises reacting allyl alcohol with a mixture of carbon monoxide and hydrogen in the presence of a solvent and a catalyst comprising a rhodium complex and a diphosphine. The diphoshine is a trans-1,2-bis(bis(3,4-di-n-alkylphenyl)phosphinomethyl)cyclobutane and/or a 2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis[bis(3,4-di-n-alkylphenyl)phosphino] butane. The process gives high yield of 4-hydroxybutyraldehyde compared to 3-hydroxy-2-methylpropionaldehyde.

  本发明涉及一种生产4-羟基丁醛的方法。该方法包括在溶剂和催化剂的存在下，将丙烯醇与一种一氧化碳和氢气的混合物反应，所述催化剂包括一个铑配合物和一个二膦。所述二膦是一种trans-1,2-双[双(3,4-二-n-烷基苯基)膦甲基]环丁烷和/或2,3-O-异丙亚甲基-2,3-双羟基-1,4-双[双(3,4-二-n-烷基苯基)膦基]丁烷。与3-羟基-2-甲基丙醛相比，该方法可高产4-羟基丁醛。
• HYDROFORMYLATION PROCESS
  申请人：Lyondell Chemical Technology, L.P.

  公开号：EP2081882B1

  公开（公告）日：2012-07-25
• Hydroformylation process
  申请人：White Daniel F.

  公开号：US20100292514A1

  公开（公告）日：2010-11-18

  A process for the production of 4-hydroxybutyraldehyde is described. The process comprises reacting allyl alcohol with a mixture of carbon monoxide and hydrogen in the presence of a solvent and a catalyst comprising a rhodium complex and a diphosphine. The diphoshine is a trans-1,2 -bis(bis(3,4-di-n-alkylphenyl)phosphinomethyl)cyclobutane and/or a 2,3-O-isopropylidene- 2,3 -dihydroxy-1,4-bis[bis(3,4-di-n-alkylphenyl)phosphino]butane. The process gives high yield of 4-hydroxybutyraldehyde compared to 3-hydroxy-2-methylpropionaldehyde.
• US7271295B1
  申请人：——

  公开号：US7271295B1

  公开（公告）日：2007-09-18